Patient P-02093
Therapy response
Unstable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
32%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S05
- Day 108 AD-05 recommended — Adherence Support AD-05
- Day 109 Patient accepted — Started AD-05 in the companion
- Day 114 No meaningful change — Adherence Support AD-05
- Day 129 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 129.
Primary contributors, last 14 days
- GI instability+12
- Nutritional resilience-9
- Inflammatory activity+6
- Toxicity+2
What helped?
- Adherence Support AD-05Day 108Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↑25
- WearableResting HR 74 bpm
- Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 3.2 · butyrate capacity 58/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 45 ms
- Sleep
- 6.5 h
- Steps
- 5,494
- Resting HR
- 72 bpm
Daily log: GI score 20, nutritional resilience 65, adherence 85.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02088 | 57% | S04 | — | — | 44 |
| P-02113 | 57% | S05 | — | — | 41 |
| P-02259 | 52% | S15 | — | — | 37 |
| P-02522 | 50% | S01 | BR-03 | no change | 40 |
| P-02087 | 49% | S01 | BR-03 | no change | 40 |
| P-02100 | 48% | S08 | — | — | 35 |
| P-02439 | 48% | S08 | BR-03 | no change | 40 |
| P-02285 | 47% | S14 | AD-05 | no change | 39 |
| P-02416 | 47% | S04 | — | — | 37 |
| P-02625 | 47% | S15 | — | — | 36 |
| P-02258 | 46% | S15 | — | — | 26 |
| P-02368 | 46% | S03 | — | — | 34 |