700 patients110,866 observations180 daysLIVE

700 trajectories across META-24

Trajectories

Synthetic demo data

All Strong responders · 180 Moderate responders · 160 Non-responders · 70 Early toxicity · 84 Late toxicity · 42 Delayed loss of response · 49 Resilient responder · 25 High response / high intolerance · 90

Mean lived trajectory vs baseline model

days with fewer than 10 patients are cut

solid = observed · dashed = predicted

Individual trajectories, highest risk first

P-02039D138 · risk 96%

UnstableUnstableresp 38

P-02165D107 · risk 74%

StableUnstableresp 59

P-02176D151 · risk 54%

StableImprovingresp 52

P-02371D169 · risk 35%

FavorableDeterioratingresp 64

P-02259D171 · risk 28%

UnstableDeterioratingresp 37

P-02150D175 · risk 23%

DecliningDeterioratingresp 45

P-02091D142 · risk 20%

ImprovingImprovingresp 57

P-02461D139 · risk 18%

ImprovingFavorableresp 56

P-02201D172 · risk 15%

UnstableImprovingresp 30

P-02384D146 · risk 13%

FavorableFavorableresp 80

P-02095D176 · risk 10%

FavorableImprovingresp 66

P-02644D168 · risk 8%

DecliningFavorableresp 65