Patient P-02305
Therapy response
Declining
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
24%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S20
- Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 12.
Primary contributors, last 14 days
- Inflammatory activity+8
- Treatment adherence+4
- GI instability+3
- Nutritional resilience+3
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑60
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 27 ms, trending down
- Autonomic recovery ↓45
- WearableResting HR 79 bpm
- WearableShort sleep window
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.0 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 38/100
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.2 · butyrate capacity 38/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 31 ms
- Sleep
- 6.4 h
- Steps
- 5,623
- Resting HR
- 76 bpm
Daily log: GI score 29, nutritional resilience 62, adherence 92.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02037 | 52% | S04 | GI-04 | improved | 53 |
| P-02158 | 52% | S20 | — | — | 43 |
| P-02513 | 49% | S16 | GI-04 | no change | 46 |
| P-02622 | 49% | S07 | — | — | 50 |
| P-02058 | 47% | S05 | GI-04 | no change | 48 |
| P-02150 | 47% | S11 | HY-01 | improved | 45 |
| P-02223 | 47% | S20 | HY-01 | improved | 49 |
| P-02351 | 47% | S16 | — | — | 51 |
| P-02417 | 47% | S18 | DT-01 | no change | 55 |
| P-02023 | 46% | S07 | — | — | 46 |
| P-02200 | 46% | S13 | — | — | 47 |
| P-02262 | 46% | S16 | — | — | 53 |