Patient P-01364
Therapy response
Stable
Tolerance
Stable
GI state
Stable
Inflammatory state
Unstable
Nutritional resilience
Stable
Discontinuation risk
71%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 51 GI-04 recommended — GI Support Protocol GI-04
- Day 52 Patient accepted — Started GI-04 in the companion
- Day 60 GI symptom burden −18% vs expected — GI Support Protocol GI-04
- Day 66 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Inflammatory activity+2
- Nutritional resilience+2
What helped?
- GI Support Protocol GI-04Day 51Result: symptom burden −18%
LIFE OS recommendation
Dietary Support Protocol NP-02
62%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 54 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 25/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 59
- WearableHRV 17 ms, trending down
- Autonomic recovery ↓25
- WearableResting HR 80 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 54
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 25/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 17 ms
- Sleep
- 6.8 h
- Steps
- 5,798
- Resting HR
- 81 bpm
Daily log: GI score 54, nutritional resilience 43, adherence 49.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01462 | 62% | S14 | NP-02 | improved | 47 |
| P-01393 | 61% | S14 | GI-04 | improved | 53 |
| P-01573 | 58% | S14 | GI-04 | improved | 49 |
| P-01496 | 57% | S14 | SC-12 | improved | 46 |
| P-01865 | 55% | S14 | NP-02 | no change | 51 |
| P-01879 | 55% | S14 | SC-12 | improved | 51 |
| P-01692 | 53% | S14 | NP-02 | improved | 49 |
| P-01465 | 50% | S14 | NP-02 | improved | 56 |
| P-01482 | 50% | S14 | GI-04 | improved | 47 |
| P-01872 | 50% | S14 | NP-02 | improved | 47 |
| P-01409 | 49% | S14 | SC-12 | improved | 41 |
| P-01576 | 49% | S14 | NP-02 | no change | 49 |