600 patients66,869 observations120 daysLIVE

600 trajectories across NBL-101

Trajectories

Synthetic demo data

All Strong responders · 132 Moderate responders · 102 Non-responders · 54 Early toxicity · 36 Late toxicity · 30 Delayed loss of response · 30 Resilient responder · 32 High response / high intolerance · 184

Mean lived trajectory vs baseline model

days with fewer than 10 patients are cut

solid = observed · dashed = predicted

Individual trajectories, highest risk first

P-01332D102 · risk 96%

StableUnstableresp 43

P-01826D103 · risk 92%

DecliningUnstableresp 42

P-01436D104 · risk 76%

UnstableDeterioratingresp 38

P-01473D119 · risk 62%

StableStableresp 51

P-01574D110 · risk 51%

StableImprovingresp 47

P-01372D117 · risk 33%

FavorableDeterioratingresp 81

P-01382D109 · risk 25%

FavorableDeterioratingresp 82

P-01832D114 · risk 21%

UnstableImprovingresp 42

P-01344D118 · risk 16%

UnstableFavorableresp 26

P-01553D119 · risk 14%

FavorableDeterioratingresp 79

P-01460D110 · risk 11%

ImprovingImprovingresp 82

P-01791D111 · risk 9%

DecliningDeterioratingresp 79