Patient P-01473
Therapy response
Stable
Tolerance
Improving
GI state
Stable
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
62%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 46 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 52 SC-12 recommended — Supportive Compound SC-12
- Day 53 Patient accepted — Started SC-12 in the companion
- Day 56 GI-04 recommended — GI Support Protocol GI-04
- Day 57 Patient accepted — Started GI-04 in the companion
- Day 59 GI symptom burden −16% vs expected — Supportive Compound SC-12
- Day 65 GI symptom burden −21% vs expected — GI Support Protocol GI-04
- Day 65 Tolerance state changed — Unstable → Improving
- Day 71 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 46.
Primary contributors, last 14 days
- Toxicity-9
- Inflammatory activity-5
- GI instability-2
- Nutritional resilience+2
What helped?
- Supportive Compound SC-12Day 52Result: symptom burden −16%
- GI Support Protocol GI-04Day 56Result: symptom burden −21%
LIFE OS recommendation
Dietary Support Protocol NP-02
53%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 49 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 33/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 48
- WearableHRV 38 ms, trending down
- Autonomic recovery ↓20
- Wearable3,821 steps/day
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 33/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 6.7 h
- Steps
- 3,859
- Resting HR
- 70 bpm
Daily log: GI score 49, nutritional resilience 44, adherence 51.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01365 | 60% | S14 | SC-12 | improved | 49 |
| P-01570 | 59% | S14 | SC-12 | improved | 46 |
| P-01339 | 57% | S14 | GI-04 | improved | 54 |
| P-01556 | 55% | S14 | GI-04 | improved | 44 |
| P-01438 | 54% | S14 | GI-04 | improved | 56 |
| P-01614 | 54% | S14 | GI-04 | improved | 53 |
| P-01323 | 53% | S14 | GI-04 | improved | 50 |
| P-01330 | 53% | S14 | GI-04 | improved | 47 |
| P-01486 | 52% | S18 | GI-04 | improved | 47 |
| P-01543 | 52% | S14 | GI-04 | improved | 54 |
| P-01307 | 50% | S14 | GI-04 | improved | 43 |
| P-01458 | 50% | S14 | GI-04 | improved | 44 |