600 patients66,869 observations120 daysLIVE

Patient P-01788

Synthetic patientNBL-101 · Day 115 · 65–74 · M · baseline S10Open companion preview
Therapy response
Declining
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
5%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S10

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • Toxicity-14
  • Inflammatory activity-12
  • GI instability-6
  • Treatment adherence+5
  • Nutritional resilience+4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients.

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity 60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling 45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Drug metabolism and exposure 40
      • DNACYP2D6 poor metabolizer → higher exposure
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.6 · butyrate capacity 51/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    68 ms
    Sleep
    6.5 h
    Steps
    5,459
    Resting HR
    58 bpm
    Daily log: GI score 14, nutritional resilience 71, adherence 94.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0140855%S0177
    P-0148054%S0680
    P-0141453%S1381
    P-0146752%S09HY-01improved79
    P-0176452%S0872
    P-0139951%S0183
    P-0159151%S0381
    P-0162251%S0377
    P-0163951%S0279
    P-0175950%S1978
    P-0130948%S1287
    P-0138248%S1582