Patient P-01816
Therapy response
Unstable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
12%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S01
- Day 84 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 84.
Primary contributors, last 14 days
- GI instability-11
- Toxicity-10
- Inflammatory activity-7
- Treatment adherence-4
- Nutritional resilience+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↑20
- Wearable2,705 steps/day
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 3.2 · butyrate capacity 54/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 7.0 h
- Steps
- 3,635
- Resting HR
- 57 bpm
Daily log: GI score 10, nutritional resilience 64, adherence 74.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01846 | 56% | S01 | — | — | 37 |
| P-01722 | 55% | S09 | — | — | 36 |
| P-01401 | 51% | S15 | — | — | 34 |
| P-01847 | 51% | S01 | — | — | 37 |
| P-01313 | 50% | S01 | BR-03 | improved | 32 |
| P-01370 | 49% | S03 | — | — | 44 |
| P-01397 | 48% | S03 | — | — | 28 |
| P-01483 | 47% | S14 | AD-05 | no change | 35 |
| P-01350 | 45% | S19 | BR-03 | no change | 34 |
| P-01832 | 45% | S18 | — | — | 42 |
| P-01345 | 44% | S12 | — | — | 30 |
| P-01541 | 43% | S09 | AD-05 | no change | 43 |