Patient P-03333
Therapy response
Improving
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
23%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S14
- Day 22 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 22 SC-12 recommended — Supportive Compound SC-12
- Day 23 Patient accepted — Started SC-12 in the companion
- Day 29 GI symptom burden −15% vs expected — Supportive Compound SC-12
- Day 35 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 22.
Primary contributors, last 14 days
- GI instability-9
- Inflammatory activity+7
- Toxicity+5
- Nutritional resilience+3
- Treatment adherence-3
What helped?
- Supportive Compound SC-12Day 22Result: symptom burden −15%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↑20
- WearableShort sleep window
- Inflammatory signalling ↑15
- WearableHRV 36 ms, trending down
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 4.1 · butyrate capacity 80/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 39 ms
- Sleep
- 6.1 h
- Steps
- 6,398
- Resting HR
- 64 bpm
Daily log: GI score 17, nutritional resilience 66, adherence 93.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.