Patient P-02203
Therapy response
Improving
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
30%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S09
- Day 11 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 11.
Primary contributors, last 14 days
- GI instability+10
- Nutritional resilience-10
- Toxicity-6
- Inflammatory activity+5
- Treatment adherence-3
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable66 min
stable · +0.1 vs previous 14 d
Sleep duration
Wearable6.6 h
stable · +0.0 vs previous 14 d
Energy level
Daily log6/10
stable · +0.1 vs previous 14 d
Steps
Wearable7,966
stable · -31 vs previous 14 d
GI burden
Companion28.9/100
improving · -2.8 vs previous 14 d
Adherence
Companion91.9 %
stable · +0.4 vs previous 14 d
Sleep quality
Wearable51.6/100
stable · +0.6 vs previous 14 d
Glucose, CGM daily mean
CGM130 mg/dL
stable · -0.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 67 from the failing basin, 21 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +4.9
- Daily walks resumedperturbation · steering +3.3
- Histamine load (supports)perturbation · steering +3.3
- Proteinsupporter · GI -2.9 next day
- Histamine loadsupporter · GI -2.1 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Low microbial diversityhidden · steering -7.7
- Simple carbohydratesperturbation · steering -4.9
- Dietary driftperturbation · steering -2.6
- Simple carbohydratesdetractor · GI +3 next day
- Dietary fat loaddetractor · GI +1.4 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+3detractor · 74%
- Protein-2.9supporter · 95%
- Histamine load-2.1supporter · 67%
- Dietary fat load+1.4detractor · 55%
- Insoluble fibre+1.3no signal · 42%
- Alcohol-0.7no signal · 21%
- Caffeine-0.6no signal · 24%
- Ultra-processed food+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 24/100
- MicrobiomeF. prausnitzii depleted
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.3 · butyrate capacity 24/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 68 ms
- Sleep
- 6.6 h
- Steps
- 8,157
- Resting HR
- 61 bpm
Daily log: GI score 29, nutritional resilience 57, adherence 92.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.