Patient P-02294
Therapy response
Favorable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
8%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S11
- Day 51 HY-01 recommended — Hydration Protocol HY-01
- Day 52 Patient accepted — Started HY-01 in the companion
- Day 56 No meaningful change — Hydration Protocol HY-01
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- Inflammatory activity-7
- GI instability-3
- Treatment adherence+3
- Toxicity-3
- Nutritional resilience+2
What helped?
- Hydration Protocol HY-01Day 51Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable62 min
worsening · -3.1 vs previous 14 d
Sleep duration
Wearable7.6 h
stable · +0.2 vs previous 14 d
Energy level
Daily log7.3/10
stable · -0.1 vs previous 14 d
Steps
Wearable6,760
stable · +17 vs previous 14 d
GI burden
Companion15.7/100
improving · -0.5 vs previous 14 d
Adherence
Companion96.6 %
stable · +1.9 vs previous 14 d
Sleep quality
Wearable61.9/100
improving · +4.0 vs previous 14 d
Glucose, CGM daily mean
CGM120 mg/dL
stable · +0.2 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 91 from the failing basin, 5 from restoration.
Good elements to keep
- Hydration Protocol HY-01intervention · steering +13.7
- Butyrate producers intacthidden · steering +7.5
- Protein (supports)perturbation · steering +7.3
- Daily walks resumedperturbation · steering +3.3
- Proteinsupporter · GI -4.4 next day
Main detractors to watch
- FUT2 non-secretorhidden · steering -10.6
- Histamine loadperturbation · steering -8.7
- Bacteroides fragilis elevatedhidden · steering -7.4
- IL6 high-expression varianthidden · steering -7.3
- Histamine loaddetractor · GI +4.9 next day
- Ultra-processed fooddetractor · GI +3.7 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+4.9detractor · 95%
- Protein-4.4supporter · 95%
- Ultra-processed food+3.7detractor · 95%
- Alcohol+3.3detractor · 87%
- Simple carbohydrates+0.7no signal · 16%
- Caffeine+0.6no signal · 15%
- Insoluble fibre-0.3no signal · 15%
- Dietary fat load0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Autonomic recovery ↑25
- WearableResting HR 72 bpm
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 3.8 · butyrate capacity 52/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 70 ms
- Sleep
- 8.0 h
- Steps
- 6,605
- Resting HR
- 70 bpm
Daily log: GI score 16, nutritional resilience 70, adherence 97.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.