Patient P-02335
Therapy response
Favorable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
17%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S04
- Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 14.
Primary contributors, last 14 days
- Nutritional resilience-6
- Treatment adherence-5
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 3.2 · butyrate capacity 70/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 64 ms
- Sleep
- 6.0 h
- Steps
- 7,877
- Resting HR
- 61 bpm
Daily log: GI score 22, nutritional resilience 59, adherence 91.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02483 | 44% | S06 | BR-03 | no change | 64 |
| P-02280 | 36% | S07 | BR-03 | no change | 50 |
| P-02282 | 33% | S01 | BR-03 | no change | 88 |
| P-02354 | 34% | S01 | CR-01 | improved | 78 |
| P-02491 | 46% | S09 | DT-01 | no change | 65 |
| P-02462 | 45% | S12 | DT-01 | improved | 65 |
| P-02518 | 39% | S17 | DT-01 | improved | 68 |
| P-02218 | 36% | S01 | DT-01 | improved | 61 |
| P-02235 | 35% | S14 | DT-01 | improved | 50 |
| P-02565 | 35% | S09 | DT-01 | no change | 79 |
| P-02586 | 35% | S18 | DT-01 | improved | 56 |
| P-02339 | 34% | S03 | DT-01 | improved | 50 |