Patient P-02367
Therapy response
Improving
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
62%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S03
- Day 111 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 111.
Primary contributors, last 14 days
- GI instability+4
- Inflammatory activity+2
- Nutritional resilience+2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
71%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 89% showed improvement
- median effect visible after 8 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 23/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 58
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 65 and rising
- Autonomic recovery ↑25
- WearableResting HR 86 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 47
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.1 · butyrate capacity 23/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 51 ms
- Sleep
- 6.3 h
- Steps
- 4,362
- Resting HR
- 84 bpm
Daily log: GI score 65, nutritional resilience 41, adherence 67.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02205 | 54% | S20 | — | — | 57 |
| P-02123 | 47% | S03 | — | — | 62 |
| P-02472 | 46% | S14 | — | — | 60 |
| P-02521 | 44% | S14 | — | — | 53 |
| P-02025 | 43% | S15 | CR-01 | improved | 61 |
| P-02398 | 43% | S06 | GI-04 | improved | 63 |
| P-02054 | 39% | S01 | CR-01 | improved | 57 |
| P-02359 | 39% | S15 | — | — | 59 |
| P-02009 | 38% | S08 | CR-01 | improved | 64 |
| P-02029 | 38% | S18 | — | — | 56 |
| P-02316 | 38% | S14 | GI-04 | improved | 51 |
| P-02401 | 38% | S14 | GI-04 | improved | 49 |