Patient P-02450
Therapy response
Declining
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
12%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S12
- Day 104 NP-02 recommended — Dietary Support Protocol NP-02
- Day 105 Patient accepted — Started NP-02 in the companion
- Day 115 GI symptom burden −16% vs expected — Dietary Support Protocol NP-02
- Day 121 Tolerance state changed — Unstable → Improving
What changed?
Trajectory is tracking the baseline prediction.
Primary contributors, last 14 days
- GI instability-11
- Toxicity+8
- Inflammatory activity+3
- Nutritional resilience+3
- Treatment adherence+3
What helped?
- Dietary Support Protocol NP-02Day 104Result: symptom burden −16%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- CYP2D6 Intermediate metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 3.2 · butyrate capacity 61/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 55 ms
- Sleep
- 6.4 h
- Steps
- 5,509
- Resting HR
- 59 bpm
Daily log: GI score 12, nutritional resilience 66, adherence 93.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02277 | 51% | S05 | AD-05 | improved | 92 |
| P-02486 | 47% | S10 | ME-01 | improved | 86 |
| P-02415 | 45% | S17 | GI-04 | improved | 86 |
| P-02193 | 44% | S11 | CR-01 | improved | 87 |
| P-02249 | 43% | S09 | DT-01 | improved | 100 |
| P-02630 | 41% | S17 | NP-02 | improved | 76 |
| P-02667 | 41% | S08 | HY-01 | improved | 77 |
| P-02068 | 39% | S14 | NP-02 | improved | 83 |
| P-02127 | 36% | S11 | SC-12 | improved | 73 |
| P-02464 | 36% | S18 | ME-01 | improved | 68 |
| P-02690 | 36% | S02 | ME-01 | improved | 73 |
| P-02441 | 31% | S11 | SC-12 | improved | 67 |