Patient P-02645
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
27%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S02
- Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 22 HY-01 recommended — Hydration Protocol HY-01
- Day 23 Patient accepted — Started HY-01 in the companion
- Day 27 GI symptom burden −24% vs expected — Hydration Protocol HY-01
- Day 33 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 14.
Primary contributors, last 14 days
- GI instability+12
- Inflammatory activity+8
- Treatment adherence+2
- Toxicity+2
What helped?
- Hydration Protocol HY-01Day 22Result: symptom burden −24%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.1 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 40/100
- Autonomic recovery ↓20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- CYP2D6 Rapid metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.1 · butyrate capacity 40/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 51 ms
- Sleep
- 6.2 h
- Steps
- 7,186
- Resting HR
- 58 bpm
Daily log: GI score 24, nutritional resilience 64, adherence 97.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02033 | 57% | S06 | GI-04 | improved | 51 |
| P-02219 | 57% | S13 | — | — | 60 |
| P-02235 | 56% | S14 | DT-01 | improved | 50 |
| P-02394 | 55% | S12 | — | — | 62 |
| P-02538 | 55% | S02 | GI-04 | improved | 59 |
| P-02697 | 55% | S07 | GI-04 | improved | 56 |
| P-02070 | 54% | S11 | — | — | 55 |
| P-02500 | 53% | S14 | GI-04 | no change | 58 |
| P-02218 | 52% | S01 | DT-01 | improved | 61 |
| P-02351 | 52% | S16 | — | — | 51 |
| P-02573 | 52% | S10 | — | — | 52 |
| P-02303 | 51% | S15 | GI-04 | improved | 48 |