DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
9/100
vs baseline (day 0)
-30
8 improved · 0 worsened
synthetic signature · consistent with this patient's biology
- 1 keystone species absent
- 3 resistance genes
Pathogens / opportunists0/5
↓ from 3
Keystone species1/8
↓ from 2
Diversity0/2
↓ from 1
Metabolic modules0/4
Vitamin synthesis1/7
Oral translocation0/1
↓ from 1
Host DNA0/1
Tissue recycling0/1
Central mechanisms0/2
Virulence factors1/1
↓ from 2
Antibiotic resistance genes3/3
↓ from 4
Genetic predisposition2/2
Opportunists above range
none
Keystone species absent
Akkermansia muciniphila
Capacity
Shannon 3.32 · butyrate 847 CPM · SCFA 1356
1 vitamins below
Host & mechanisms
tissue recycling 29/100
oral translocation 1.5% AR
3 resistance genes · 1 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 0.575 % AR · in range | 0.548 % AR · in range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 3.034 % AR · above range | 0.014 % AR · in range(improved) | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 5.057 % AR · above range | 0.025 % AR · in range(improved) | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 1.011 % AR · above range | 0.039 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.027 % AR · in range | 0.045 % AR · in range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0.22 % AR · in range(improved) | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.44 % AR · in range | 0.33 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 1.24 % AR · in range | 0.77 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.75 % AR · in range | 0.37 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.56 % AR · in range | 0.16 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 0.8 % AR · in range | 1.09 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.88 % AR · in range | 0.34 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 2.96 · below range | 3.32 · in range(improved) | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 132 specii · in range | 156 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 747 CPM · in range | 847 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1180 CPM · in range | 1356 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 436 CPM · in range | 473 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 122 CPM · in range | 138 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 421 CPM · below range | 198 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 2761 CPM · in range | 4440 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 3471 CPM · in range | 3719 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 2969 CPM · in range | 4211 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 4206 CPM · in range | 3591 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3065 CPM · in range | 3777 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 3529 CPM · in range | 2818 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 2.33 % AR · above range | 1.5 % AR · in range(improved) | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 163 pb · in range | 159 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 26 /100 · in range | 29 /100 · in range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 57 /100 · in range | 50 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 54 /100 · in range | 49 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 2
| fimD outer membrane usher | 84 potriviri/M · present | 26 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 63 potriviri/M · present | resolved(resolved) | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 4
| sul1 | 1 citiri/M · present | 5.1 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 8 citiri/M · present | 1.7 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 3.8 citiri/M · present | 5.4 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 5.2 citiri/M · present | resolved(resolved) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| IL6 | 2.45 OR · risk variant | 1.75 OR · risk variant | expected reference genotype | Higher inflammatory tone |
| CYP2D6 | 2.24 OR · risk variant | 2.74 OR · risk variant | expected reference genotype | Expected exposure |