Patient P-01328
Synthetic patientNBL-101 · Day 102 · 55–64 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
92%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 44 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 46 SC-12 recommended — Supportive Compound SC-12
- Day 47 Patient accepted — Started SC-12 in the companion
- Day 53 No meaningful change — Supportive Compound SC-12
- Day 56 GI-04 recommended — GI Support Protocol GI-04
- Day 57 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 44.
Primary contributors, last 14 days
- Toxicity-4
- Treatment adherence-3
- Nutritional resilience+2
What helped?
- Supportive Compound SC-12Day 46Result: no meaningful change
- GI Support Protocol GI-04Day 56Declined by patient
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion64.5/100
worsening · +5.2 vs previous 14 d
Toxicity
Blood44.7/100
worsening · +2.6 vs previous 14 d
Sleep quality
Wearable31.4/100
stable · +0.7 vs previous 14 d
Energy level
Daily log2.5/10
worsening · -0.2 vs previous 14 d
Stress level
Daily log6.6/10
worsening · +0.4 vs previous 14 d
Steps
Wearable3,914
worsening · -567 vs previous 14 d
Adherence
Companion46.6 %
worsening · -5.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 28 from the failing basin, 65 from restoration.
Would help
Would not help
- SC-12 Supportive Compoundalready tried, no meaningful change
- Keep fat lowGI +6.5 next day on high-intake days · n 29
- Keep histamine lowGI +5.7 next day on high-intake days · n 24
- Keep simple carbs lowGI +5.3 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.5detractor · 95%
- Histamine load+5.7detractor · 95%
- Simple carbohydrates+5.3detractor · 95%
- Insoluble fibre+3.7detractor · 77%
- Alcohol+3detractor · 70%
- Spicy / capsaicin+2.7no signal · 45%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 65 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 44/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑50
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 58
- Autonomic recovery ↑45
- WearableResting HR 73 bpm
- Wearable3,914 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 45
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.7 · butyrate capacity 44/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 49 ms
- Sleep
- 6.9 h
- Steps
- 3,391
- Resting HR
- 74 bpm
Daily log: GI score 65, nutritional resilience 29, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.