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Patient P-01340

Synthetic patientNBL-101 · Day 116 · 45–54 · M · baseline S09Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
24%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S09
  2. Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days
  • Treatment adherence-5
  • GI instability+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    22.8/100
    worsening · +1.4 vs previous 14 d
    Toxicity
    Blood
    30.1/100
    worsening · +1.5 vs previous 14 d
    Sleep quality
    Wearable
    35.8/100
    stable · -1.4 vs previous 14 d
    Energy level
    Daily log
    4.3/10
    worsening · -0.3 vs previous 14 d
    Stress level
    Daily log
    3.9/10
    stable · +0.1 vs previous 14 d
    Steps
    Wearable
    3,701
    stable · -54 vs previous 14 d
    Adherence
    Companion
    86.8 %
    improving · +5.2 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 60 from the failing basin, 49 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Nothing clearly counter-productive in the record.
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Alcohol
      +1.8no signal · 55%
    • Insoluble fibre
      -1.6no signal · 40%
    • Histamine load
      +0.7no signal · 17%
    • Dietary fat load
      +0.6no signal · 17%
    • Simple carbohydrates
      -0.3no signal · 15%
    • Spicy / capsaicin
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling ↓45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Drug metabolism and exposure ↑35
      • DNADPYD *2A → slower clearance
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery ↓20
      • Wearable3,701 steps/day
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 4.4 · butyrate capacity 52/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    41 ms
    Sleep
    7.1 h
    Steps
    4,640
    Resting HR
    64 bpm
    Daily log: GI score 23, nutritional resilience 62, adherence 87.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0173144%S01ME-01improved32
    P-0177342%S05AD-05improved27
    P-0131336%S01BR-03improved32
    P-0132034%S09HY-01improved38
    P-0161834%S10GI-04improved39
    P-0134232%S11DT-01improved48
    P-0134632%S12DT-01improved52
    P-0138332%S14NP-02improved40
    P-0143032%S05CR-01improved54
    P-0137431%S08HY-01improved49
    P-0140531%S14SC-12improved44
    P-0143231%S14GI-04improved46