Patient P-01348
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
62%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S11
- Day 87 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 87.
Primary contributors, last 14 days
- GI instability+24
- Nutritional resilience-21
- Inflammatory activity+17
- Toxicity+16
- Treatment adherence+4
What helped?
No interventions yet.
LIFE OS recommendation
Hydration Protocol HY-01
49%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 56% showed improvement
- median effect visible after 4 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion42/100
worsening · +5.5 vs previous 14 d
Toxicity
Blood30/100
worsening · +10.0 vs previous 14 d
Sleep quality
Wearable48.2/100
stable · -2.7 vs previous 14 d
Energy level
Daily log4.3/10
worsening · -0.9 vs previous 14 d
Stress level
Daily log5.4/10
worsening · +0.5 vs previous 14 d
Steps
Wearable5,550
worsening · -913 vs previous 14 d
Adherence
Companion85.2 %
stable · -0.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 38 from the failing basin, 62 from restoration.
Would help
Would not help
- Nothing clearly counter-productive in the record.
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+2.5no signal · 46%
- Alcohol-1no signal · 17%
- Insoluble fibre-0.9no signal · 18%
- Histamine load+0.7no signal · 15%
- Simple carbohydrates-0.5no signal · 15%
- Spicy / capsaicin0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑25
- BloodInflammatory load index 41
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 4.2 · butyrate capacity 79/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 66 ms
- Sleep
- 7.6 h
- Steps
- 6,097
- Resting HR
- 60 bpm
Daily log: GI score 42, nutritional resilience 50, adherence 85.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01731 | 34% | S01 | ME-01 | improved | 32 |
| P-01313 | 33% | S01 | BR-03 | improved | 32 |
| P-01321 | 32% | S12 | GI-04 | improved | 53 |
| P-01342 | 31% | S11 | DT-01 | improved | 48 |
| P-01383 | 31% | S14 | NP-02 | improved | 40 |
| P-01773 | 31% | S05 | AD-05 | improved | 27 |
| P-01405 | 30% | S14 | SC-12 | improved | 44 |
| P-01752 | 30% | S20 | DT-01 | improved | 50 |
| P-01861 | 30% | S12 | HY-01 | improved | 47 |
| P-01432 | 29% | S14 | GI-04 | improved | 46 |
| P-01618 | 29% | S10 | GI-04 | improved | 39 |
| P-01374 | 28% | S08 | HY-01 | improved | 49 |