Patient P-01360
Synthetic patientNBL-101 · Day 93 · 25–34 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
78%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 59 GI-04 recommended — GI Support Protocol GI-04
- Day 60 Patient accepted — Started GI-04 in the companion
- Day 68 GI symptom burden −28% vs expected — GI Support Protocol GI-04
- Day 74 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Treatment adherence-9
- GI instability+6
- Toxicity+4
- Inflammatory activity+3
- Nutritional resilience-2
What helped?
- GI Support Protocol GI-04Day 59Result: symptom burden −28%
LIFE OS recommendation
Dietary Support Protocol NP-02
62%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion59.1/100
worsening · +5.5 vs previous 14 d
Toxicity
Blood47.8/100
worsening · +4.1 vs previous 14 d
Sleep quality
Wearable33/100
worsening · -4.3 vs previous 14 d
Energy level
Daily log3/10
worsening · -0.7 vs previous 14 d
Stress level
Daily log6.7/10
worsening · +0.3 vs previous 14 d
Steps
Wearable6,545
stable · +54 vs previous 14 d
Adherence
Companion47.3 %
worsening · -18.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 31 from the failing basin, 61 from restoration.
Would help
Would not help
- Keep fat lowGI +6.4 next day on high-intake days · n 25
- Keep fibre lowGI +4.9 next day on high-intake days · n 23
- Keep simple carbs lowGI +3.1 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.4detractor · 95%
- Insoluble fibre+4.9detractor · 95%
- Simple carbohydrates+3.1detractor · 72%
- Histamine load-2.8no signal · 44%
- Alcohol+1.1no signal · 21%
- Spicy / capsaicin+0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 59 and rising
- WearableSleep 5.9 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 24/100
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑55
- DNADPYD *2A → slower clearance
- BloodToxicity index 48
- Inflammatory signalling ↑45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 59
- Autonomic recovery ↓45
- WearableResting HR 73 bpm
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2 · butyrate capacity 24/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 48 ms
- Sleep
- 6.1 h
- Steps
- 6,542
- Resting HR
- 73 bpm
Daily log: GI score 59, nutritional resilience 40, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01465 | 55% | S14 | NP-02 | improved | 56 |
| P-01494 | 55% | S14 | GI-04 | improved | 42 |
| P-01433 | 53% | S14 | GI-04 | improved | 48 |
| P-01570 | 53% | S14 | SC-12 | improved | 46 |
| P-01339 | 52% | S14 | GI-04 | improved | 54 |
| P-01554 | 51% | S05 | GI-04 | improved | 47 |
| P-01539 | 50% | S14 | GI-04 | improved | 43 |
| P-01781 | 50% | S14 | NP-02 | improved | 45 |
| P-01786 | 50% | S07 | ME-01 | improved | 46 |
| P-01834 | 50% | S14 | NP-02 | improved | 44 |
| P-01447 | 49% | S15 | GI-04 | improved | 44 |
| P-01547 | 49% | S13 | GI-04 | improved | 50 |