600 patients66,869 observations120 daysLIVE

Patient P-01361

Synthetic patientNBL-101 · Day 116 · 45–54 · M · baseline S04Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
21%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S04

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • Toxicity+26
  • Nutritional resilience-9
  • Treatment adherence+4
  • Inflammatory activity+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    25.2/100
    worsening · +3.6 vs previous 14 d
    Toxicity
    Blood
    32.9/100
    worsening · +6.5 vs previous 14 d
    Sleep quality
    Wearable
    45.8/100
    worsening · -5.1 vs previous 14 d
    Energy level
    Daily log
    4.9/10
    worsening · -0.9 vs previous 14 d
    Stress level
    Daily log
    4.3/10
    worsening · +0.3 vs previous 14 d
    Steps
    Wearable
    5,336
    stable · -18 vs previous 14 d
    Adherence
    Companion
    97.9 %
    stable · +1.7 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 67 from the failing basin, 23 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep histamine low
      GI +2.3 next day on high-intake days · n 16
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +2.3detractor · 89%
    • Simple carbohydrates
      -1.4no signal · 51%
    • Spicy / capsaicin
      +1.4no signal · 54%
    • Alcohol
      +1.3no signal · 50%
    • Insoluble fibre
      -0.9no signal · 30%
    • Dietary fat load
      -0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity 60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling 60
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 35 ms, trending down
    • Autonomic recovery 25
      • WearableResting HR 78 bpm
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 4.5 · butyrate capacity 52/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    36 ms
    Sleep
    7.3 h
    Steps
    6,012
    Resting HR
    76 bpm
    Daily log: GI score 25, nutritional resilience 57, adherence 98.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0153760%S0453
    P-0134354%S0455
    P-0180454%S19AD-05improved61
    P-0156952%S0458
    P-0168451%S1359
    P-0153850%S1556
    P-0148549%S17GI-04no change63
    P-0149949%S0265
    P-0152649%S1452
    P-0162149%S0457
    P-0148148%S0354
    P-0165348%S0862