Patient P-01363

Synthetic patientNBL-101 · Day 108 · 55–64 · F · baseline S11Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Deteriorating

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

20%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S11
Day 30 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 30.

Primary contributors, last 14 days

Toxicity+8
Nutritional resilience+5
GI instability+2
Inflammatory activity+2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

21.4/100

improving · -6.8 vs previous 14 d

Toxicity

Blood

18.1/100

worsening · +4.2 vs previous 14 d

Sleep quality

Wearable

26.9/100

improving · +5.3 vs previous 14 d

Energy level

Daily log

5.1/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

4.2/10

improving · -0.3 vs previous 14 d

Steps

Wearable

7,042

improving · +719 vs previous 14 d

Adherence

Companion

84.2 %

stable · -1.0 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 62 from the failing basin, 49 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Nothing clearly counter-productive in the record.

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
-0.7no signal · 18%
Insoluble fibre
-0.5no signal · 15%
Spicy / capsaicin
+0.3no signal · 15%
Simple carbohydrates
-0.2no signal · 15%
Alcohol
-0.2no signal · 15%
Histamine load
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↓45
- WearableResting HR 76 bpm
- WearableShort sleep window
Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.9 h, below personal baseline
Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose

Microbiome

Shannon diversity 4.3 · butyrate capacity 70/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 41 ms
Sleep: 6.1 h
Steps: 6,772
Resting HR: 74 bpm

Daily log: GI score 21, nutritional resilience 67, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01773	45%	S05	AD-05	improved	27
P-01731	44%	S01	ME-01	improved	32
P-01313	38%	S01	BR-03	improved	32
P-01320	35%	S09	HY-01	improved	38
P-01342	35%	S11	DT-01	improved	48
P-01346	34%	S12	DT-01	improved	52
P-01618	34%	S10	GI-04	improved	39
P-01374	32%	S08	HY-01	improved	49
P-01430	32%	S05	CR-01	improved	54
P-01593	32%	S10	HY-01	improved	56
P-01752	32%	S20	DT-01	improved	50
P-01861	32%	S12	HY-01	improved	47