Patient P-01377

Synthetic patientNBL-101 · Day 115 · 35–44 · F · baseline S11Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Improving

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

17%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S11
Day 72 AD-05 recommended — Adherence Support AD-05
Day 73 Patient accepted — Started AD-05 in the companion
Day 78 No meaningful change — Adherence Support AD-05
Day 94 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 94.

Primary contributors, last 14 days

Nutritional resilience+10
Toxicity-6
GI instability-5

What helped?

Adherence Support AD-05Day 72
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

19.1/100

improving · -5.7 vs previous 14 d

Toxicity

Blood

16.3/100

improving · -1.5 vs previous 14 d

Sleep quality

Wearable

52.9/100

improving · +5.6 vs previous 14 d

Energy level

Daily log

6.3/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

3.3/10

improving · -0.2 vs previous 14 d

Steps

Wearable

8,119

stable · +199 vs previous 14 d

Adherence

Companion

81.6 %

stable · -2.5 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 65 from the failing basin, 36 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5
Adherence Support AD-05
intervention · steering +4.3
Daily walks resumed
perturbation · steering +3.3

Main detractors to watch

Low-HRV stretch
perturbation · steering -2.7
Dietary drift
perturbation · steering -2.6

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+1.2no signal · 27%
Histamine load
+1.1no signal · 26%
Simple carbohydrates
+0.9no signal · 27%
Spicy / capsaicin
-0.8no signal · 24%
Alcohol
-0.6no signal · 16%
Insoluble fibre
+0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.4 · butyrate capacity 47/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 64 ms
Sleep: 7.4 h
Steps: 8,205
Resting HR: 67 bpm

Daily log: GI score 19, nutritional resilience 70, adherence 82.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01829	54%	S11	—	—	31
P-01719	53%	S11	—	—	41
P-01483	52%	S14	AD-05	no change	35
P-01415	49%	S12	—	—	32
P-01370	48%	S03	—	—	44
P-01541	48%	S09	AD-05	no change	43
P-01313	47%	S01	BR-03	improved	32
P-01846	47%	S01	—	—	37
P-01450	46%	S09	BR-03	no change	36
P-01847	44%	S01	—	—	37
P-01892	44%	S20	—	—	52
P-01350	43%	S19	BR-03	no change	34