Patient P-01384
Therapy response
Improving
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
9%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S08
- Day 19 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 19.
Primary contributors, last 14 days
- Toxicity+6
- GI instability-3
- Inflammatory activity+3
- Treatment adherence+3
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion11/100
improving · -7.8 vs previous 14 d
Toxicity
Blood19.2/100
worsening · +2.3 vs previous 14 d
Sleep quality
Wearable41.3/100
improving · +1.5 vs previous 14 d
Energy level
Daily log6.2/10
improving · +0.5 vs previous 14 d
Stress level
Daily log4.3/10
improving · -0.2 vs previous 14 d
Steps
Wearable7,554
stable · +75 vs previous 14 d
Adherence
Companion94.7 %
stable · +2.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 93 from the failing basin, 8 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More simple carbsGI -3.7 next day on high-intake days · n 16
Would not help
- HY-01 Hydration Protocolonly 44% improved among 9 similar
- Keep spicy lowGI +5.2 next day on high-intake days · n 15
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Spicy / capsaicin+5.2detractor · 95%
- Simple carbohydrates-3.7supporter · 63%
- Dietary fat load-2.4no signal · 34%
- Alcohol+1.5no signal · 32%
- Insoluble fibre-0.5no signal · 15%
- Histamine load-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↓45
- WearableResting HR 74 bpm
- WearableShort sleep window
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Mucosal barrier integrity ↓10
- WearableSleep 6.1 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 4.4 · butyrate capacity 73/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 51 ms
- Sleep
- 5.9 h
- Steps
- 7,148
- Resting HR
- 74 bpm
Daily log: GI score 11, nutritional resilience 63, adherence 95.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.