Patient P-01389
Synthetic patientNBL-101 · Day 116 · 65–74 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
65%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 46 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 46 SC-12 recommended — Supportive Compound SC-12
- Day 47 Patient accepted — Started SC-12 in the companion
- Day 50 GI-04 recommended — GI Support Protocol GI-04
- Day 51 Patient accepted — Started GI-04 in the companion
- Day 53 GI symptom burden −18% vs expected — Supportive Compound SC-12
- Day 59 No meaningful change — GI Support Protocol GI-04
- Day 59 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 46.
Primary contributors, last 14 days
- GI instability-16
- Inflammatory activity-16
- Treatment adherence+12
- Nutritional resilience+3
What helped?
- Supportive Compound SC-12Day 46Result: symptom burden −18%
- GI Support Protocol GI-04Day 50Result: no meaningful change
LIFE OS recommendation
Dietary Support Protocol NP-02
53%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion47.9/100
improving · -5.5 vs previous 14 d
Toxicity
Blood48.8/100
worsening · +9.1 vs previous 14 d
Sleep quality
Wearable9.1/100
improving · +1.0 vs previous 14 d
Energy level
Daily log2.1/10
worsening · -0.1 vs previous 14 d
Stress level
Daily log5/10
stable · +0.0 vs previous 14 d
Steps
Wearable549
worsening · -219 vs previous 14 d
Adherence
Companion51.2 %
improving · +4.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 38 from the failing basin, 49 from restoration.
Would help
Would not help
- GI-04 GI Support Protocolalready tried, no meaningful change
- Keep fat lowGI +3.4 next day on high-intake days · n 22
- Keep histamine lowGI +3.1 next day on high-intake days · n 21
- Keep fibre lowGI +2.7 next day on high-intake days · n 12
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+3.4detractor · 95%
- Histamine load+3.1detractor · 95%
- Insoluble fibre+2.7detractor · 95%
- Simple carbohydrates+2.4detractor · 91%
- Spicy / capsaicin-0.8no signal · 24%
- Alcohol+0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 48 and rising
- WearableSleep 4.4 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 42/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑65
- WearableResting HR 77 bpm
- Wearable549 steps/day
- WearableShort sleep window
- Inflammatory signalling ↓45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 45
- Drug metabolism and exposure ↑20
- BloodToxicity index 49
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.6 · butyrate capacity 42/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 55 ms
- Sleep
- 5.3 h
- Steps
- 1,170
- Resting HR
- 79 bpm
Daily log: GI score 48, nutritional resilience 40, adherence 51.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.