Patient P-01405
Synthetic patientNBL-101 · Day 118 · 65–74 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Stable
Discontinuation risk
44%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 GI symptom burden −20% vs expected — Dietary Support Protocol NP-02
- Day 44 SC-12 recommended — Supportive Compound SC-12
- Day 45 Patient accepted — Started SC-12 in the companion
- Day 48 Tolerance state changed — Unstable → Improving
- Day 51 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 51 GI symptom burden −23% vs expected — Supportive Compound SC-12
- Day 57 Tolerance state changed — Unstable → Improving
- Day 60 GI-04 recommended — GI Support Protocol GI-04
- Day 61 Patient accepted — Started GI-04 in the companion
- Day 69 GI symptom burden −22% vs expected — GI Support Protocol GI-04
- Day 75 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 51.
Primary contributors, last 14 days
- Treatment adherence+9
- Toxicity+5
- GI instability-3
What helped?
- Dietary Support Protocol NP-02Day 31Result: symptom burden −20%
- Supportive Compound SC-12Day 44Result: symptom burden −23%
- GI Support Protocol GI-04Day 60Result: symptom burden −22%
LIFE OS recommendation
Behavioural Recommendation BR-03
30%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 20% showed improvement
- median effect visible after 7 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion32.5/100
stable · -0.6 vs previous 14 d
Toxicity
Blood28/100
improving · -3.3 vs previous 14 d
Sleep quality
Wearable41/100
stable · -1.6 vs previous 14 d
Energy level
Daily log5.1/10
stable · +0.1 vs previous 14 d
Stress level
Daily log4.1/10
stable · -0.1 vs previous 14 d
Steps
Wearable9,714
stable · -177 vs previous 14 d
Adherence
Companion63.8 %
stable · +1.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 54 from the failing basin, 39 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- Keep fibre lowGI +2 next day on high-intake days · n 18
- Keep fat lowGI +1.8 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Insoluble fibre+2detractor · 76%
- Dietary fat load+1.8detractor · 66%
- Histamine load+1.2no signal · 39%
- Simple carbohydrates+1.2no signal · 53%
- Spicy / capsaicin+0.7no signal · 33%
- Alcohol-0.6no signal · 19%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 34/100
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↑45
- WearableResting HR 73 bpm
- WearableShort sleep window
- Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.4 · butyrate capacity 34/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 61 ms
- Sleep
- 6.6 h
- Steps
- 9,022
- Resting HR
- 72 bpm
Daily log: GI score 33, nutritional resilience 56, adherence 64.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.