Patient P-01407
Synthetic patientNBL-101 · Day 108 · 65–74 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 No meaningful change — Dietary Support Protocol NP-02
- Day 48 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 52 GI-04 recommended — GI Support Protocol GI-04
- Day 53 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 48.
Primary contributors, last 14 days
- Toxicity+10
- GI instability+9
- Nutritional resilience-8
- Treatment adherence-4
- Inflammatory activity+2
What helped?
- Dietary Support Protocol NP-02Day 31Result: no meaningful change
- GI Support Protocol GI-04Day 52Declined by patient
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion77/100
worsening · +13.7 vs previous 14 d
Toxicity
Blood56.6/100
worsening · +3.6 vs previous 14 d
Sleep quality
Wearable8.6/100
worsening · -5.6 vs previous 14 d
Energy level
Daily log1.2/10
worsening · -0.8 vs previous 14 d
Stress level
Daily log7.8/10
worsening · +0.6 vs previous 14 d
Steps
Wearable395
worsening · -458 vs previous 14 d
Adherence
Companion40.6 %
stable · -0.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 23 from the failing basin, 82 from restoration.
Would help
Would not help
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep fat lowGI +4.7 next day on high-intake days · n 21
- Keep fibre lowGI +3.7 next day on high-intake days · n 18
- Keep simple carbs lowGI +3 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.7detractor · 95%
- Insoluble fibre+3.7detractor · 94%
- Alcohol+3.2no signal · 54%
- Simple carbohydrates+3detractor · 84%
- Spicy / capsaicin+1.4no signal · 34%
- Histamine load-0.7no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↓65
- WearableResting HR 74 bpm
- Wearable395 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 77 and rising
- WearableSleep 5.2 h, below personal baseline
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 67
- WearableHRV 20 ms, trending down
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 57
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 30/100
- Daily logFibre intake low in recent food logs
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 2.4 · butyrate capacity 30/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 25 ms
- Sleep
- 5.5 h
- Steps
- 962
- Resting HR
- 75 bpm
Daily log: GI score 77, nutritional resilience 29, adherence 41.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01386 | 16% | S13 | — | — | 70 |
| P-01352 | 16% | S20 | — | — | 70 |
| P-01699 | 21% | S04 | GI-04 | improved | 69 |
| P-01508 | 17% | S18 | — | — | 68 |
| P-01509 | 17% | S17 | — | — | 68 |
| P-01817 | 17% | S14 | — | — | 67 |
| P-01877 | 22% | S01 | CR-01 | improved | 67 |
| P-01515 | 16% | S16 | — | — | 66 |
| P-01629 | 17% | S19 | — | — | 66 |
| P-01714 | 19% | S14 | GI-04 | improved | 66 |
| P-01858 | 25% | S14 | NP-02 | improved | 65 |
| P-01317 | 17% | S19 | — | — | 65 |