Patient P-01421

Synthetic patientNBL-101 · Day 103 · 35–44 · M · baseline S11Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S11

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Nutritional resilience+11
Inflammatory activity-3
Treatment adherence+3
GI instability-2
Toxicity-2

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

14.1/100

worsening · +1.1 vs previous 14 d

Toxicity

Blood

11.2/100

worsening · +3.8 vs previous 14 d

Sleep quality

Wearable

48.5/100

stable · +1.6 vs previous 14 d

Energy level

Daily log

6.5/10

stable · -0.1 vs previous 14 d

Stress level

Daily log

4.1/10

worsening · +0.2 vs previous 14 d

Steps

Wearable

4,879

stable · +32 vs previous 14 d

Adherence

Companion

92.6 %

improving · +4.6 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 94 from the failing basin, 8 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5

Main detractors to watch

IL6 high-expression variant
hidden · steering -7.3
Antibiotic course
perturbation · steering -4.7
Alcohol
perturbation · steering -3.9
Spicy / capsaicin
perturbation · steering -3.9
Alcohol
detractor · GI +2.5 next day
Spicy / capsaicin
detractor · GI +2.5 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+2.5detractor · 84%
Spicy / capsaicin
+2.5detractor · 90%
Simple carbohydrates
-0.7no signal · 21%
Histamine load
+0.5no signal · 15%
Insoluble fibre
-0.2no signal · 15%
Dietary fat load
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓25
- DNAIL6 -174 variant raises baseline inflammatory tone
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.7 · butyrate capacity 62/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 47 ms
Sleep: 6.8 h
Steps: 5,343
Resting HR: 70 bpm

Daily log: GI score 14, nutritional resilience 69, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01766	42%	S05	AD-05	no change	90
P-01804	26%	S19	AD-05	improved	61
P-01541	23%	S09	AD-05	no change	43
P-01329	44%	S08	BR-03	improved	79
P-01495	43%	S07	BR-03	improved	85
P-01677	39%	S05	BR-03	no change	86
P-01654	50%	S08	CR-01	improved	85
P-01430	24%	S05	CR-01	improved	54
P-01479	36%	S15	DT-01	improved	84
P-01855	33%	S04	DT-01	improved	73
P-01767	28%	S14	DT-01	no change	63
P-01724	27%	S10	DT-01	improved	63