Patient P-01428

Synthetic patientNBL-101 · Day 114 · 65–74 · M · baseline S19Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S19

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Nutritional resilience+9
Treatment adherence-8
GI instability-4
Inflammatory activity+3
Toxicity+3

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

0/100

worsening · +0.6 vs previous 14 d

Toxicity

Blood

17.9/100

worsening · +4.4 vs previous 14 d

Sleep quality

Wearable

36.9/100

stable · -0.5 vs previous 14 d

Energy level

Daily log

6.9/10

worsening · -0.3 vs previous 14 d

Stress level

Daily log

4.3/10

stable · +0.0 vs previous 14 d

Steps

Wearable

8,620

worsening · -633 vs previous 14 d

Adherence

Companion

90 %

stable · -3.7 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 108 from the failing basin, 23 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5

Main detractors to watch

Bacteroides fragilis elevated
hidden · steering -7.4
Low-HRV stretch
perturbation · steering -2.7
Dietary drift
perturbation · steering -2.6
Alcohol on dosing days
perturbation · steering -1.8

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Insoluble fibre
+1.8no signal · 25%
Histamine load
-0.7no signal · 15%
Simple carbohydrates
+0.7no signal · 15%
Spicy / capsaicin
-0.4no signal · 15%
Dietary fat load
+0.3no signal · 15%
Alcohol
-0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↑20
- WearableShort sleep window
Mucosal barrier integrity ↓10
- WearableSleep 6.1 h, below personal baseline

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4 · butyrate capacity 80/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 39 ms
Sleep: 6.2 h
Steps: 7,277
Resting HR: 65 bpm

Daily log: GI score 0, nutritional resilience 77, adherence 90.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01766	42%	S05	AD-05	no change	90
P-01804	26%	S19	AD-05	improved	61
P-01495	45%	S07	BR-03	improved	85
P-01329	39%	S08	BR-03	improved	79
P-01677	38%	S05	BR-03	no change	86
P-01654	45%	S08	CR-01	improved	85
P-01430	23%	S05	CR-01	improved	54
P-01479	38%	S15	DT-01	improved	84
P-01855	33%	S04	DT-01	improved	73
P-01724	28%	S10	DT-01	improved	63
P-01767	27%	S14	DT-01	no change	63
P-01346	25%	S12	DT-01	improved	52