Patient P-01439

Synthetic patientNBL-101 · Day 92 · 25–34 · M · baseline S18Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Improving

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S18
Day 48 ME-01 recommended — Monitoring Escalation ME-01
Day 49 Patient accepted — Started ME-01 in the companion
Day 52 Deterioration detected before clinical escalation — Monitoring Escalation ME-01

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Toxicity-15
Nutritional resilience+8
GI instability-6
Inflammatory activity-4
Treatment adherence+2

What helped?

Monitoring Escalation ME-01Day 48
Result: deterioration detected before clinical escalation

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

13.8/100

worsening · +2.0 vs previous 14 d

Toxicity

Blood

7.5/100

improving · -1.8 vs previous 14 d

Sleep quality

Wearable

55.2/100

stable · +0.8 vs previous 14 d

Energy level

Daily log

6.9/10

stable · +0.2 vs previous 14 d

Stress level

Daily log

3.4/10

stable · +0.1 vs previous 14 d

Steps

Wearable

8,117

worsening · -458 vs previous 14 d

Adherence

Companion

97.9 %

stable · +1.4 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 89 from the failing basin, 4 from restoration.

Good elements to keep

Monitoring Escalation ME-01
intervention · steering +25
Butyrate producers intact
hidden · steering +7.5
Dietary fat load (supports)
perturbation · steering +4.1
Daily walks resumed
perturbation · steering +3.3
Dietary fat load
supporter · GI -2.8 next day

Main detractors to watch

Rapid metabolizer
hidden · steering -8
Bacteroides fragilis elevated
hidden · steering -7.4
Alcohol
perturbation · steering -7
Alcohol on dosing days
perturbation · steering -1.8
Alcohol
detractor · GI +4.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
+4.3detractor · 95%
Dietary fat load
-2.8supporter · 66%
Insoluble fibre
+0.9no signal · 27%
Simple carbohydrates
-0.3no signal · 15%
Spicy / capsaicin
-0.3no signal · 15%
Histamine load
-0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Rapid metabolizer
Expected exposure

Microbiome

Shannon diversity 4.3 · butyrate capacity 76/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 64 ms
Sleep: 7.2 h
Steps: 8,862
Resting HR: 55 bpm

Daily log: GI score 14, nutritional resilience 70, adherence 98.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01467	52%	S09	HY-01	improved	79
P-01625	49%	S06	SC-12	improved	83
P-01329	47%	S08	BR-03	improved	79
P-01671	47%	S04	SC-12	improved	90
P-01791	44%	S06	ME-01	improved	79
P-01479	42%	S15	DT-01	improved	84
P-01855	42%	S04	DT-01	improved	73
P-01654	41%	S08	CR-01	improved	85
P-01796	41%	S09	SC-12	improved	86
P-01495	39%	S07	BR-03	improved	85
P-01798	39%	S08	NP-02	improved	78
P-01763	38%	S16	ME-01	improved	100