DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
30/100
vs baseline (day 0)
+17
1 improved · 9 worsened
synthetic signature · consistent with this patient's biology
- 2 opportunists above range: Klebsiella pneumoniae, Streptococcus gallolyticus
- 2 keystone species absent
- 6 resistance genes
Pathogens / opportunists2/5
↑ from 1
Keystone species2/8
↑ from 1
Diversity0/2
Metabolic modules0/4
Vitamin synthesis2/7
↑ from 1
Oral translocation1/1
↑ from 0
Host DNA0/1
Tissue recycling0/1
Central mechanisms0/2
Virulence factors2/2
↑ from 1
Antibiotic resistance genes6/6
↑ from 3
Genetic predisposition2/2
Opportunists above range
Klebsiella pneumoniae 3.956% AR
Streptococcus gallolyticus 1.319% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum
Capacity
Shannon 3.08 · butyrate 707 CPM · SCFA 1148
2 vitamins below
Host & mechanisms
tissue recycling 35/100
oral translocation 3.02% AR
6 resistance genes · 2 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 0.668 % AR · in range | 0.641 % AR · in range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 0.026 % AR · in range | 3.956 % AR · above range(worsened) | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 3.355 % AR · above range | 0.219 % AR · in range(improved) | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.053 % AR · in range | 1.319 % AR · above range(worsened) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.068 % AR · in range | 0.062 % AR · in range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0.59 % AR · in range | 0 % AR · absent(worsened) | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.14 % AR · in range | 1.24 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.4 % AR · in range | 0.69 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.45 % AR · in range | 1.3 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.6 % AR · in range | 1.43 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 0.8 % AR · in range | 0.34 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 1.18 % AR · in range | 0.62 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 3.33 · in range | 3.08 · in range | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 143 specii · in range | 129 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 860 CPM · in range | 707 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1313 CPM · in range | 1148 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 457 CPM · in range | 381 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 97 CPM · in range | 119 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 394 CPM · below range | 497 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 2936 CPM · in range | 319 CPM · below range(worsened) | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 3605 CPM · in range | 3203 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 4082 CPM · in range | 3471 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 3219 CPM · in range | 2979 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3395 CPM · in range | 4272 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 3623 CPM · in range | 3592 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 1.56 % AR · in range | 3.02 % AR · above range(worsened) | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 160 pb · in range | 157 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 27 /100 · in range | 35 /100 · in range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 47 /100 · in range | 56 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 57 /100 · in range | 56 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 2
| fimD outer membrane usher | 39 potriviri/M · present | 46 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | — | 42 potriviri/M · present(new) | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 6
| sul1 | 3.9 citiri/M · present | 7.8 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 7.2 citiri/M · present | 5.8 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 6.1 citiri/M · present | 6.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | — | 3.3 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
| aadA | — | 1.5 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
| dfrA1 | — | 3 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| DPYD | 2.73 OR · risk variant | 2.5 OR · risk variant | expected reference genotype | Slower drug clearance |
| CYP2D6 | 3.14 OR · risk variant | 2.92 OR · risk variant | expected reference genotype | Expected exposure |