DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
40/100
vs baseline (day 0)
+23
1 improved · 7 worsened
synthetic signature · consistent with this patient's biology
- 3 opportunists above range: Escherichia coli, Klebsiella pneumoniae, Clostridioides difficile
- 2 keystone species absent
- Shannon 2.94 (expected ≥ 3)
- 4 resistance genes
Pathogens / opportunists3/5
↑ from 0
Keystone species2/8
↑ from 1
Diversity1/2
↑ from 0
Metabolic modules0/4
Vitamin synthesis2/7
↑ from 1
Oral translocation1/1
Host DNA0/1
Tissue recycling0/1
Central mechanisms0/2
Virulence factors2/2
↑ from 1
Antibiotic resistance genes4/4
↓ from 5
Genetic predisposition1/1
Opportunists above range
Escherichia coli 10.608% AR
Klebsiella pneumoniae 3.182% AR
Clostridioides difficile 1.061% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum
Capacity
Shannon 2.94 · butyrate 741 CPM · SCFA 1202
2 vitamins below
Host & mechanisms
tissue recycling 30/100
oral translocation 2.44% AR
4 resistance genes · 2 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 0.392 % AR · in range | 10.608 % AR · above range(worsened) | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 0.026 % AR · in range | 3.182 % AR · above range(worsened) | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 0.174 % AR · in range | 0.293 % AR · in range | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.072 % AR · in range | 0.042 % AR · in range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.004 % AR · in range | 1.061 % AR · above range(worsened) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0.45 % AR · in range | 0 % AR · absent(worsened) | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.77 % AR · in range | 0.14 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.5 % AR · in range | 0.82 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.43 % AR · in range | 0.18 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.62 % AR · in range | 0.11 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 0.16 % AR · in range | 0.29 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.57 % AR · in range | 0.39 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 3.31 · in range | 2.94 · below range(worsened) | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 150 specii · in range | 132 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 799 CPM · in range | 741 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1294 CPM · in range | 1202 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 427 CPM · in range | 397 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 105 CPM · in range | 112 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 487 CPM · below range | 267 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 3127 CPM · in range | 446 CPM · below range(worsened) | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 3063 CPM · in range | 3665 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 3162 CPM · in range | 2821 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 3004 CPM · in range | 2721 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3785 CPM · in range | 2501 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 2770 CPM · in range | 3253 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 2.02 % AR · above range | 2.44 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 164 pb · in range | 157 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 26 /100 · in range | 30 /100 · in range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 52 /100 · in range | 54 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 53 /100 · in range | 54 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 2
| fimD outer membrane usher | 64 potriviri/M · present | 47 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | — | 63 potriviri/M · present(new) | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 5
| sul1 | 8.2 citiri/M · present | 1.3 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 1.1 citiri/M · present | 3 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 8.2 citiri/M · present | 2.7 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 3.1 citiri/M · present | 3.4 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | 3.8 citiri/M · present | resolved(resolved) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 1
| CYP2D6 | 2.72 OR · risk variant | 2.87 OR · risk variant | expected reference genotype | Expected exposure |