Patient P-01467

Synthetic patientNBL-101 · Day 116 · 45–54 · M · baseline S09Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Improving

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S09
Day 26 HY-01 recommended — Hydration Protocol HY-01
Day 27 Patient accepted — Started HY-01 in the companion
Day 31 GI symptom burden −10% vs expected — Hydration Protocol HY-01
Day 37 Tolerance state changed — Unstable → Improving

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days

Toxicity-8
Nutritional resilience+6
Treatment adherence-4
GI instability-3

What helped?

Hydration Protocol HY-01Day 26
Result: symptom burden −10%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

9.4/100

improving · -0.7 vs previous 14 d

Toxicity

Blood

1.1/100

improving · -6.9 vs previous 14 d

Sleep quality

Wearable

50.5/100

stable · -0.0 vs previous 14 d

Energy level

Daily log

6.9/10

improving · +0.3 vs previous 14 d

Stress level

Daily log

2.9/10

improving · -0.2 vs previous 14 d

Steps

Wearable

5,778

stable · -13 vs previous 14 d

Adherence

Companion

92.1 %

stable · -0.1 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 94 from the failing basin, 10 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

HY-01 Hydration Protocol
already tried, no meaningful change

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Alcohol
-1.6no signal · 38%
Dietary fat load
-1.3no signal · 28%
Histamine load
+1.3no signal · 28%
Insoluble fibre
+1.2no signal · 19%
Simple carbohydrates
+0.6no signal · 15%
Spicy / capsaicin
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

CYP2D6 Rapid metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.3 · butyrate capacity 75/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 60 ms
Sleep: 6.1 h
Steps: 5,829
Resting HR: 59 bpm

Daily log: GI score 9, nutritional resilience 74, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01439	52%	S18	ME-01	improved	79
P-01625	46%	S06	SC-12	improved	83
P-01671	46%	S04	SC-12	improved	90
P-01796	43%	S09	SC-12	improved	86
P-01329	41%	S08	BR-03	improved	79
P-01479	40%	S15	DT-01	improved	84
P-01654	40%	S08	CR-01	improved	85
P-01791	40%	S06	ME-01	improved	79
P-01798	38%	S08	NP-02	improved	78
P-01855	38%	S04	DT-01	improved	73
P-01495	37%	S07	BR-03	improved	85
P-01763	36%	S16	ME-01	improved	100