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Patient P-01468

Synthetic patientNBL-101 · Day 105 · 65–74 · F · baseline S06Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
4%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S06
  2. Day 72 BR-03 recommended — Behavioural Recommendation BR-03
  3. Day 73 Patient accepted — Started BR-03 in the companion
  4. Day 80 No meaningful change — Behavioural Recommendation BR-03
  5. Day 85 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 85.

Primary contributors, last 14 days
  • GI instability-31
  • Inflammatory activity-18
  • Nutritional resilience+12
  • Toxicity-3

What helped?

  • Behavioural Recommendation BR-03Day 72
    Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
0/100
improving · -21.9 vs previous 14 d
Toxicity
Blood
13.8/100
improving · -8.0 vs previous 14 d
Sleep quality
Wearable
36.8/100
improving · +12.6 vs previous 14 d
Energy level
Daily log
6/10
improving · +1.3 vs previous 14 d
Stress level
Daily log
2.2/10
improving · -1.4 vs previous 14 d
Steps
Wearable
9,518
improving · +1,079 vs previous 14 d
Adherence
Companion
85 %
stable · -0.4 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 87 from the failing basin, 42 from restoration.

Good elements to keep
  • Butyrate producers intact
    hidden · steering +7.5
  • Behavioural Recommendation BR-03
    intervention · steering +7.3
  • Daily walks resumed
    perturbation · steering +3.3
Main detractors to watch
  • Histamine load
    perturbation · steering -11.9
  • FUT2 non-secretor
    hidden · steering -10.6
  • Enterobacteriaceae elevated
    hidden · steering -7.4
  • Poor-sleep week
    perturbation · steering -3
  • Histamine load
    detractor · GI +7.7 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Histamine load
    +7.7detractor · 95%
  • Alcohol
    -2.2no signal · 38%
  • Spicy / capsaicin
    -2no signal · 29%
  • Simple carbohydrates
    -1.7no signal · 23%
  • Dietary fat load
    +0.6no signal · 15%
  • Insoluble fibre
    -0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓40
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • WearableSleep 5.9 h, below personal baseline
  • Autonomic recovery ↑20
    • WearableShort sleep window
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 3.6 · butyrate capacity 57/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
50 ms
Sleep
6.2 h
Steps
9,159
Resting HR
56 bpm
Daily log: GI score 0, nutritional resilience 73, adherence 85.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Keep fibre steady; no new sources this week
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0188245%S18——44
P-0145043%S09BR-03no change36
P-0182943%S11——31
P-0132042%S09HY-01improved38
P-0189942%S08——37
P-0137741%S11AD-05no change42
P-0184741%S01——37
P-0137040%S03——44
P-0189240%S20——52
P-0141539%S12——32
P-0154139%S09AD-05no change43
P-0184639%S01——37