Patient P-01468

Synthetic patientNBL-101 · Day 105 · 65–74 · F · baseline S06Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S06
Day 72 BR-03 recommended — Behavioural Recommendation BR-03
Day 73 Patient accepted — Started BR-03 in the companion
Day 80 No meaningful change — Behavioural Recommendation BR-03
Day 85 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 85.

Primary contributors, last 14 days

GI instability-31
Inflammatory activity-18
Nutritional resilience+12
Toxicity-3

What helped?

Behavioural Recommendation BR-03Day 72
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

0/100

improving · -21.9 vs previous 14 d

Toxicity

Blood

13.8/100

improving · -8.0 vs previous 14 d

Sleep quality

Wearable

36.8/100

improving · +12.6 vs previous 14 d

Energy level

Daily log

6/10

improving · +1.3 vs previous 14 d

Stress level

Daily log

2.2/10

improving · -1.4 vs previous 14 d

Steps

Wearable

9,518

improving · +1,079 vs previous 14 d

Adherence

Companion

85 %

stable · -0.4 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 87 from the failing basin, 42 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5
Behavioural Recommendation BR-03
intervention · steering +7.3
Daily walks resumed
perturbation · steering +3.3

Main detractors to watch

Histamine load
perturbation · steering -11.9
FUT2 non-secretor
hidden · steering -10.6
Enterobacteriaceae elevated
hidden · steering -7.4
Poor-sleep week
perturbation · steering -3
Histamine load
detractor · GI +7.7 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+7.7detractor · 95%
Alcohol
-2.2no signal · 38%
Spicy / capsaicin
-2no signal · 29%
Simple carbohydrates
-1.7no signal · 23%
Dietary fat load
+0.6no signal · 15%
Insoluble fibre
-0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓40
- DNAFUT2 non-secretor lowers mucosal fucosylation
- WearableSleep 5.9 h, below personal baseline
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 3.6 · butyrate capacity 57/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 50 ms
Sleep: 6.2 h
Steps: 9,159
Resting HR: 56 bpm

Daily log: GI score 0, nutritional resilience 73, adherence 85.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01320	42%	S09	HY-01	improved	38
P-01618	38%	S10	GI-04	improved	39
P-01313	37%	S01	BR-03	improved	32
P-01374	36%	S08	HY-01	improved	49
P-01555	36%	S06	GI-04	improved	56
P-01346	35%	S12	DT-01	improved	52
P-01385	35%	S06	HY-01	improved	50
P-01455	35%	S01	GI-04	improved	61
P-01861	35%	S12	HY-01	improved	47
P-01724	34%	S10	DT-01	improved	63
P-01593	33%	S10	HY-01	improved	56
P-01731	32%	S01	ME-01	improved	32