Patient P-01470
Synthetic patientNBL-101 · Day 112 · 25–34 · F · baseline S16Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Unstable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
59%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S16
- Day 83 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 83.
Primary contributors, last 14 days
- Toxicity+17
- Treatment adherence-7
- GI instability-5
- Inflammatory activity+4
- Nutritional resilience-2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
66%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion58.1/100
improving · -6.8 vs previous 14 d
Toxicity
Blood65/100
worsening · +5.7 vs previous 14 d
Sleep quality
Wearable12.8/100
improving · +0.9 vs previous 14 d
Energy level
Daily log1.8/10
stable · +0.0 vs previous 14 d
Stress level
Daily log6.7/10
stable · +0.1 vs previous 14 d
Steps
Wearable1,796
improving · +320 vs previous 14 d
Adherence
Companion70.4 %
worsening · -14.7 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 32 from the failing basin, 63 from restoration.
Would help
Would not help
- Keep fat lowGI +6.6 next day on high-intake days · n 26
- Keep histamine lowGI +5.9 next day on high-intake days · n 22
- Keep simple carbs lowGI +5.5 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.6detractor · 95%
- Histamine load+5.9detractor · 95%
- Simple carbohydrates+5.5detractor · 95%
- Alcohol-2.3no signal · 39%
- Insoluble fibre+0.5no signal · 15%
- Spicy / capsaicin+0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 58 and rising
- WearableSleep 5.4 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 36/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓65
- WearableResting HR 74 bpm
- Wearable1,796 steps/day
- WearableShort sleep window
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 65
- WearableHRV 38 ms, trending down
- Drug metabolism and exposure ↑20
- BloodToxicity index 65
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.2 · butyrate capacity 36/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 38 ms
- Sleep
- 5.6 h
- Steps
- 2,331
- Resting HR
- 72 bpm
Daily log: GI score 58, nutritional resilience 37, adherence 70.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.