600 patients66,869 observations120 daysLIVE

Patient P-01478

Synthetic patientNBL-101 · Day 108 · 35–44 · F · baseline S18Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
45%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S18
  2. Day 77 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 77.

Primary contributors, last 14 days
  • GI instability+21
  • Nutritional resilience-8
  • Toxicity-7
  • Inflammatory activity+6

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    28.8/100
    worsening · +6.1 vs previous 14 d
    Toxicity
    Blood
    16.9/100
    worsening · +7.1 vs previous 14 d
    Sleep quality
    Wearable
    78.3/100
    worsening · -3.2 vs previous 14 d
    Energy level
    Daily log
    6.1/10
    worsening · -0.4 vs previous 14 d
    Stress level
    Daily log
    4.5/10
    worsening · +0.7 vs previous 14 d
    Steps
    Wearable
    8,640
    stable · -347 vs previous 14 d
    Adherence
    Companion
    88.3 %
    stable · +1.7 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 64 from the failing basin, 28 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep alcohol low
      GI +6.3 next day on high-intake days · n 17
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Alcohol
      +6.3detractor · 95%
    • Dietary fat load
      -2.3no signal · 40%
    • Simple carbohydrates
      -1.2no signal · 19%
    • Insoluble fibre
      -0.7no signal · 15%
    • Spicy / capsaicin
      +0.3no signal · 15%
    • Histamine load
      -0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure 40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Autonomic recovery 25
      • WearableResting HR 76 bpm
    • Inflammatory signalling 20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.4 · butyrate capacity 74/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    67 ms
    Sleep
    7.9 h
    Steps
    8,461
    Resting HR
    76 bpm
    Daily log: GI score 29, nutritional resilience 56, adherence 88.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0133549%S0445
    P-0185048%S1859
    P-0169447%S1865
    P-0189347%S1354
    P-0172946%S0865
    P-0174246%S1861
    P-0160945%S12GI-04no change48
    P-0180745%S1055
    P-0132644%S1665
    P-0144544%S1358
    P-0157144%S13SC-12improved57
    P-0164244%S1152