Patient P-01503

Synthetic patientNBL-101 · Day 111 · 25–34 · F · baseline S15Steering view · 3D Open companion preview

Therapy response

Favorable

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

51%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S15
Day 17 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 34 ME-01 recommended — Monitoring Escalation ME-01
Day 35 Patient accepted — Started ME-01 in the companion
Day 38 Deterioration detected before clinical escalation — Monitoring Escalation ME-01

What changed?

Trajectory began diverging from predicted response on Day 17.

Primary contributors, last 14 days

GI instability+25
Nutritional resilience-13
Inflammatory activity+5
Treatment adherence+3
Toxicity+3

What helped?

Monitoring Escalation ME-01Day 34
Result: deterioration detected before clinical escalation

LIFE OS recommendation

Clinician Review CR-01

72%

probability of meaningful tolerance improvement

284 similar trajectories
100% showed improvement
median effect visible after 5 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

31/100

improving · -3.6 vs previous 14 d

Toxicity

Blood

24.8/100

worsening · +10.3 vs previous 14 d

Sleep quality

Wearable

43.8/100

improving · +2.9 vs previous 14 d

Energy level

Daily log

4.8/10

worsening · -0.5 vs previous 14 d

Stress level

Daily log

4.4/10

worsening · +0.3 vs previous 14 d

Steps

Wearable

9,965

stable · +363 vs previous 14 d

Adherence

Companion

96.2 %

stable · +0.1 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 77 from the failing basin, 15 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

HY-01 Hydration Protocol
only 38% improved among 8 similar

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Simple carbohydrates
-1.6no signal · 35%
Insoluble fibre
+1.2no signal · 28%
Dietary fat load
-0.7no signal · 16%
Histamine load
+0.5no signal · 15%
Spicy / capsaicin
+0.5no signal · 15%
Alcohol
-0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↑25
- DNAIL6 -174 variant raises baseline inflammatory tone

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 4.4 · butyrate capacity 60/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 44 ms
Sleep: 6.7 h
Steps: 9,730
Resting HR: 65 bpm

Daily log: GI score 31, nutritional resilience 56, adherence 96.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01766	37%	S05	AD-05	no change	90
P-01804	31%	S19	AD-05	improved	61
P-01329	44%	S08	BR-03	improved	79
P-01677	41%	S05	BR-03	no change	86
P-01495	37%	S07	BR-03	improved	85
P-01689	26%	S13	BR-03	no change	50
P-01654	37%	S08	CR-01	improved	85
P-01430	26%	S05	CR-01	improved	54
P-01479	42%	S15	DT-01	improved	84
P-01855	38%	S04	DT-01	improved	73
P-01767	32%	S14	DT-01	no change	63
P-01724	29%	S10	DT-01	improved	63