600 patients66,869 observations120 daysLIVE

Patient P-01506

Synthetic patientNBL-101 · Day 119 · 35–44 · M · baseline S10Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
4%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S10
  2. Day 15 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days
  • GI instability-15
  • Toxicity+12
  • Inflammatory activity-10
  • Nutritional resilience+7

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    2.1/100
    improving · -3.6 vs previous 14 d
    Toxicity
    Blood
    20.1/100
    stable · +0.5 vs previous 14 d
    Sleep quality
    Wearable
    68.7/100
    improving · +2.2 vs previous 14 d
    Energy level
    Daily log
    7.8/10
    stable · +0.1 vs previous 14 d
    Stress level
    Daily log
    4.1/10
    stable · -0.1 vs previous 14 d
    Steps
    Wearable
    4,312
    improving · +528 vs previous 14 d
    Adherence
    Companion
    94.3 %
    stable · +2.1 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards restoration · 100 from the failing basin, 18 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • HY-01 Hydration Protocol
      only 44% improved among 9 similar
    • Keep spicy low
      GI +4.7 next day on high-intake days · n 22
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Spicy / capsaicin
      +4.7detractor · 95%
    • Histamine load
      -2.5no signal · 41%
    • Insoluble fibre
      +2.5no signal · 40%
    • Alcohol
      -2.5no signal · 52%
    • Dietary fat load
      -1.5no signal · 31%
    • Simple carbohydrates
      -0.7no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling 60
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 35 ms, trending down
    • Drug metabolism and exposure 35
      • DNADPYD *2A → slower clearance
    • Butyrate / short-chain fatty acid production 25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3.5 · butyrate capacity 66/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    38 ms
    Sleep
    7.1 h
    Steps
    4,034
    Resting HR
    67 bpm
    Daily log: GI score 2, nutritional resilience 78, adherence 94.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0176328%S16ME-01improved100
    P-0130234%S11SC-12no change94
    P-0168733%S1294
    P-0173038%S1793
    P-0172333%S1293
    P-0185732%S0492
    P-0132230%S0191
    P-0166236%S0291
    P-0152033%S0990
    P-0135440%S0390
    P-0176635%S05AD-05no change90
    P-0184035%S0390