Patient P-01511
Synthetic patientNBL-101 · Day 118 · 35–44 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 54 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 57 GI-04 recommended — GI Support Protocol GI-04
- Day 58 Patient accepted — Started GI-04 in the companion
- Day 63 ME-01 recommended — Monitoring Escalation ME-01
- Day 64 Patient accepted — Started ME-01 in the companion
- Day 66 GI symptom burden −20% vs expected — GI Support Protocol GI-04
- Day 67 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
- Day 72 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 54.
Primary contributors, last 14 days
- GI instability+34
- Inflammatory activity+19
- Nutritional resilience-19
- Toxicity-9
- Treatment adherence+7
What helped?
- GI Support Protocol GI-04Day 57Result: symptom burden −20%
- Monitoring Escalation ME-01Day 63Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
63%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion71.9/100
worsening · +8.8 vs previous 14 d
Toxicity
Blood37.8/100
improving · -6.7 vs previous 14 d
Sleep quality
Wearable24.1/100
stable · -0.1 vs previous 14 d
Energy level
Daily log2.9/10
stable · +0.0 vs previous 14 d
Stress level
Daily log7.4/10
worsening · +0.4 vs previous 14 d
Steps
Wearable3,156
stable · +84 vs previous 14 d
Adherence
Companion51.5 %
worsening · -2.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 42 from the failing basin, 69 from restoration.
Would help
Would not help
- Keep fat lowGI +4.6 next day on high-intake days · n 15
- Keep simple carbs lowGI +4.4 next day on high-intake days · n 19
- Keep alcohol lowGI +4.2 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.6detractor · 95%
- Simple carbohydrates+4.4detractor · 95%
- Alcohol+4.2detractor · 95%
- Histamine load+4.1detractor · 95%
- Insoluble fibre-2no signal · 28%
- Spicy / capsaicin-0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 72 and rising
- WearableSleep 6.1 h, below personal baseline
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 63
- WearableHRV 38 ms, trending down
- Autonomic recovery ↓65
- WearableResting HR 72 bpm
- Wearable3,156 steps/day
- WearableShort sleep window
- Butyrate / short-chain fatty acid production ↓20
- Daily logFibre intake low in recent food logs
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
Microbiome
Shannon diversity 2.8 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 6.1 h
- Steps
- 3,920
- Resting HR
- 69 bpm
Daily log: GI score 72, nutritional resilience 38, adherence 52.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.