Patient P-01518
Therapy response
Unstable
Tolerance
Stable
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Stable
Discontinuation risk
59%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 45 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 54 GI-04 recommended — GI Support Protocol GI-04
- Day 55 Patient accepted — Started GI-04 in the companion
- Day 63 GI symptom burden −34% vs expected — GI Support Protocol GI-04
- Day 68 ME-01 recommended — Monitoring Escalation ME-01
- Day 69 Tolerance state changed — Unstable → Improving
- Day 69 Patient accepted — Started ME-01 in the companion
- Day 72 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 45.
Primary contributors, last 14 days
- GI instability-5
- Nutritional resilience+3
- Toxicity+3
- Inflammatory activity-2
What helped?
- GI Support Protocol GI-04Day 54Result: symptom burden −34%
- Monitoring Escalation ME-01Day 68Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
52%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion37.8/100
improving · -4.9 vs previous 14 d
Toxicity
Blood44.1/100
improving · -6.2 vs previous 14 d
Sleep quality
Wearable29.5/100
stable · -0.0 vs previous 14 d
Energy level
Daily log3.1/10
improving · +0.3 vs previous 14 d
Stress level
Daily log6.2/10
improving · -0.5 vs previous 14 d
Steps
Wearable9,134
improving · +414 vs previous 14 d
Adherence
Companion47.3 %
stable · +1.3 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 41 from the failing basin, 49 from restoration.
Would help
Would not help
- Keep fat lowGI +4.3 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.3detractor · 95%
- Insoluble fibre+0.9no signal · 15%
- Alcohol+0.9no signal · 26%
- Spicy / capsaicin-0.9no signal · 22%
- Histamine load-0.7no signal · 21%
- Simple carbohydrates+0.7no signal · 17%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 26/100
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↑45
- WearableResting HR 78 bpm
- WearableShort sleep window
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.0 h, below personal baseline
- Inflammatory signalling ↓40
- BloodInflammatory load index 44
- WearableHRV 25 ms, trending down
- Drug metabolism and exposure ↑20
- BloodToxicity index 44
DNA
Fictional pharmacogenomic panel
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 3 · butyrate capacity 26/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 22 ms
- Sleep
- 6.5 h
- Steps
- 8,654
- Resting HR
- 77 bpm
Daily log: GI score 38, nutritional resilience 52, adherence 47.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01699 | 26% | S04 | GI-04 | improved | 69 |
| P-01508 | 23% | S18 | — | — | 68 |
| P-01509 | 23% | S17 | — | — | 68 |
| P-01877 | 24% | S01 | CR-01 | improved | 67 |
| P-01629 | 23% | S19 | — | — | 66 |
| P-01714 | 30% | S14 | GI-04 | improved | 66 |
| P-01858 | 32% | S14 | NP-02 | improved | 65 |
| P-01317 | 24% | S19 | — | — | 65 |
| P-01643 | 24% | S17 | — | — | 65 |
| P-01417 | 30% | S14 | GI-04 | improved | 65 |
| P-01511 | 30% | S14 | GI-04 | improved | 65 |
| P-01499 | 23% | S02 | — | — | 65 |