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Patient P-01522

Synthetic patientNBL-101 · Day 111 · 35–44 · F · baseline S06Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
11%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S06
  2. Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 14 DT-01 recommended — Dosing / Timing Recommendation DT-01
  4. Day 15 Patient accepted — Started DT-01 in the companion
  5. Day 20 No meaningful change — Dosing / Timing Recommendation DT-01

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days
  • GI instability-8
  • Inflammatory activity-3
  • Nutritional resilience-3
  • Toxicity+2

What helped?

  • Dosing / Timing Recommendation DT-01Day 14
    Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
16.1/100
worsening · +4.8 vs previous 14 d
Toxicity
Blood
14.7/100
improving · -2.3 vs previous 14 d
Sleep quality
Wearable
50.4/100
stable · -1.5 vs previous 14 d
Energy level
Daily log
6.8/10
stable · -0.1 vs previous 14 d
Stress level
Daily log
3.1/10
worsening · +0.2 vs previous 14 d
Steps
Wearable
10,388
stable · -261 vs previous 14 d
Adherence
Companion
92.5 %
stable · -1.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 78 from the failing basin, 17 from restoration.

Good elements to keep
  • Dosing / Timing Recommendation DT-01
    intervention · steering +6.9
Main detractors to watch
  • Low butyrate capacity
    hidden · steering -17.5
  • Poor metabolizer
    hidden · steering -12.7
  • Histamine load
    perturbation · steering -12.1
  • Simple carbohydrates
    perturbation · steering -10.7
  • Histamine load
    detractor · GI +6.2 next day
  • Dietary fat load
    detractor · GI +6 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Histamine load
    +6.2detractor · 95%
  • Dietary fat load
    +6detractor · 95%
  • Simple carbohydrates
    +6detractor · 95%
  • Spicy / capsaicin
    +5.4detractor · 95%
  • Alcohol
    +1.2no signal · 22%
  • Insoluble fibre
    +1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Drug metabolism and exposure ↑40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Butyrate / short-chain fatty acid production ↓35
    • MicrobiomeButyrate capacity 28/100
  • Mucosal barrier integrity ↓30
    • DNAFUT2 non-secretor lowers mucosal fucosylation
  • Inflammatory signalling ↓25
    • DNAIL6 -174 variant raises baseline inflammatory tone
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • IL6 -174 G/C
    Higher inflammatory tone
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
Microbiome
Shannon diversity 2.7 · butyrate capacity 28/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
57 ms
Sleep
7.0 h
Steps
9,169
Resting HR
59 bpm
Daily log: GI score 16, nutritional resilience 62, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0155552%S06GI-04improved56
P-0163349%S16GI-04no change55
P-0175247%S20DT-01improved50
P-0182047%S17——53
P-0145546%S01GI-04improved61
P-0151346%S19GI-04no change53
P-0159646%S08——51
P-0138544%S06HY-01improved50
P-0148744%S03——48
P-0160944%S12GI-04no change48
P-0166644%S03——55
P-0137443%S08HY-01improved49