600 patients66,869 observations120 daysLIVE

Patient P-01524

Synthetic patientNBL-101 · Day 119 · 65–74 · F · baseline S15Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Improving
Discontinuation risk
19%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S15
  2. Day 13 Trajectory diverged from predictionObserved response fell below the model's expected path.
  3. Day 90 ME-01 recommendedMonitoring Escalation ME-01
  4. Day 91 Patient declinedNot now

What changed?

Trajectory began diverging from predicted response on Day 13.

Primary contributors, last 14 days
  • Nutritional resilience+7
  • Inflammatory activity+3
  • Treatment adherence-2

What helped?

  • Monitoring Escalation ME-01Day 90
    Declined by patient
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
19.9/100
worsening · +5.4 vs previous 14 d
Toxicity
Blood
15.5/100
improving · -7.9 vs previous 14 d
Sleep quality
Wearable
66.9/100
improving · +3.8 vs previous 14 d
Energy level
Daily log
6.4/10
stable · +0.1 vs previous 14 d
Stress level
Daily log
4/10
worsening · +0.2 vs previous 14 d
Steps
Wearable
8,942
stable · -124 vs previous 14 d
Adherence
Companion
80.7 %
stable · +1.7 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 67 from the failing basin, 42 from restoration.

Good elements to keep
  • Butyrate producers intact
    hidden · steering +7.5
Main detractors to watch
  • Poor metabolizer
    hidden · steering -12.7
  • FUT2 non-secretor
    hidden · steering -10.6
  • Enterobacteriaceae elevated
    hidden · steering -7.4
  • Histamine load
    perturbation · steering -6.4
  • Histamine load
    detractor · GI +3.8 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Histamine load
    +3.8detractor · 95%
  • Insoluble fibre
    -1.4no signal · 34%
  • Alcohol
    +0.9no signal · 25%
  • Spicy / capsaicin
    -0.9no signal · 22%
  • Simple carbohydrates
    -0.1no signal · 15%
  • Dietary fat load
    0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity 60
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Drug metabolism and exposure 40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Autonomic recovery 25
    • WearableResting HR 75 bpm
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
Microbiome
Shannon diversity 4 · butyrate capacity 51/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisNormal
  • Bifidobacterium longumLow
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
53 ms
Sleep
8.1 h
Steps
9,051
Resting HR
75 bpm
Daily log: GI score 20, nutritional resilience 70, adherence 81.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Keep fibre steady; no new sources this week
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

PatientSimilarityBaselineInterventionOutcomeResponse today
P-0153021%S1683
P-0138421%S0882
P-0146021%S1282
P-0152521%S1982
P-0142222%S1680
P-0155221%S1979
P-0147121%S1979
P-0130621%S0279
P-0143921%S18ME-01improved79
P-0146721%S09HY-01improved79
P-0148921%S0278
P-0137821%S0877