Patient P-01534
Therapy response
Stable
Tolerance
Improving
GI state
Stable
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
55%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 49 SC-12 recommended — Supportive Compound SC-12
- Day 50 Patient accepted — Started SC-12 in the companion
- Day 56 GI symptom burden −19% vs expected — Supportive Compound SC-12
- Day 57 GI-04 recommended — GI Support Protocol GI-04
- Day 58 Patient accepted — Started GI-04 in the companion
- Day 62 Tolerance state changed — Unstable → Improving
- Day 66 GI symptom burden −22% vs expected — GI Support Protocol GI-04
- Day 72 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Inflammatory activity-13
- Toxicity-12
- Treatment adherence+4
What helped?
- Supportive Compound SC-12Day 49Result: symptom burden −19%
- GI Support Protocol GI-04Day 57Result: symptom burden −22%
LIFE OS recommendation
Dietary Support Protocol NP-02
55%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion46.5/100
improving · -4.6 vs previous 14 d
Toxicity
Blood27/100
improving · -8.4 vs previous 14 d
Sleep quality
Wearable31.9/100
improving · +1.8 vs previous 14 d
Energy level
Daily log3.3/10
improving · +0.4 vs previous 14 d
Stress level
Daily log5.9/10
improving · -0.5 vs previous 14 d
Steps
Wearable3,503
improving · +226 vs previous 14 d
Adherence
Companion55.4 %
stable · -0.6 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 46 from the failing basin, 43 from restoration.
Good elements to keep
- GI Support Protocol GI-04intervention · steering +33.8
- Supportive Compound SC-12intervention · steering +31.9
- Daily walks resumedperturbation · steering +3.3
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- FUT2 non-secretorhidden · steering -10.6
- Bacteroides fragilis elevatedhidden · steering -7.4
- Histamine loadperturbation · steering -7.4
- Histamine loaddetractor · GI +4 next day
- Dietary fat loaddetractor · GI +3.8 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+4detractor · 95%
- Dietary fat load+3.8detractor · 95%
- Insoluble fibre+1.6no signal · 41%
- Alcohol-1no signal · 28%
- Simple carbohydrates-0.4no signal · 15%
- Spicy / capsaicin+0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 47 and rising
- WearableSleep 6.1 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 36/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓65
- WearableResting HR 75 bpm
- Wearable3,503 steps/day
- WearableShort sleep window
- Inflammatory signalling ↓35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 29 ms, trending down
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 36/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 27 ms
- Sleep
- 5.7 h
- Steps
- 3,266
- Resting HR
- 76 bpm
Daily log: GI score 47, nutritional resilience 43, adherence 55.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.