600 patients66,869 observations120 daysLIVE

Patient P-01535

Synthetic patientNBL-101 · Day 113 · 65–74 · M · baseline S19Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
7%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S19
  2. Day 18 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 18.

Primary contributors, last 14 days
  • GI instability-26
  • Nutritional resilience+18
  • Inflammatory activity-11
  • Treatment adherence-5
  • Toxicity-5

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    8.8/100
    worsening · +4.2 vs previous 14 d
    Toxicity
    Blood
    12.4/100
    stable · +0.0 vs previous 14 d
    Sleep quality
    Wearable
    68/100
    stable · -2.5 vs previous 14 d
    Energy level
    Daily log
    7.6/10
    stable · -0.3 vs previous 14 d
    Stress level
    Daily log
    3.5/10
    stable · +0.1 vs previous 14 d
    Steps
    Wearable
    2,859
    worsening · -243 vs previous 14 d
    Adherence
    Companion
    89.5 %
    stable · -0.2 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards restoration · 92 from the failing basin, 12 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More simple carbs
      GI -3.3 next day on high-intake days · n 16
    Would not help
    • Keep histamine low
      GI +7.1 next day on high-intake days · n 27
    • Keep alcohol low
      GI +4.5 next day on high-intake days · n 19
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +7.1detractor · 95%
    • Alcohol
      +4.5detractor · 77%
    • Simple carbohydrates
      -3.3supporter · 59%
    • Dietary fat load
      +2.3no signal · 33%
    • Spicy / capsaicin
      +1.7no signal · 26%
    • Insoluble fibre
      -1.6no signal · 24%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity 30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Inflammatory signalling 20
      • MicrobiomeBacteroides fragilis expansion
    • Autonomic recovery 20
      • Wearable2,859 steps/day
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 4.3 · butyrate capacity 60/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    45 ms
    Sleep
    7.9 h
    Steps
    3,306
    Resting HR
    71 bpm
    Daily log: GI score 9, nutritional resilience 73, adherence 90.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0166449%S0380
    P-0185549%S04DT-01improved73
    P-0147548%S0476
    P-0130845%S0477
    P-0147944%S15DT-01improved84
    P-0170044%S0977
    P-0137843%S0877
    P-0147143%S1979
    P-0141142%S1884
    P-0145342%S1970
    P-0148942%S0278
    P-0150642%S1076