600 patients66,869 observations120 daysLIVE

Patient P-01552

Synthetic patientNBL-101 · Day 119 · 75+ · F · baseline S19Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
19%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S19

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • GI instability+12
  • Toxicity-11
  • Inflammatory activity+6
  • Nutritional resilience-5
  • Treatment adherence+3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    11.9/100
    worsening · +1.2 vs previous 14 d
    Toxicity
    Blood
    5.7/100
    worsening · +0.7 vs previous 14 d
    Sleep quality
    Wearable
    47.8/100
    worsening · -2.4 vs previous 14 d
    Energy level
    Daily log
    7.3/10
    stable · -0.1 vs previous 14 d
    Stress level
    Daily log
    3.3/10
    worsening · +0.3 vs previous 14 d
    Steps
    Wearable
    3,241
    stable · -64 vs previous 14 d
    Adherence
    Companion
    93.3 %
    stable · -1.1 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 92 from the failing basin, 7 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep histamine low
      GI +3.8 next day on high-intake days · n 19
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +3.8detractor · 95%
    • Dietary fat load
      +1.4no signal · 28%
    • Simple carbohydrates
      -0.5no signal · 15%
    • Insoluble fibre
      -0.4no signal · 15%
    • Spicy / capsaicin
      +0.4no signal · 15%
    • Alcohol
      0no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling 45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Drug metabolism and exposure 40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Mucosal barrier integrity 30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Autonomic recovery 20
      • Wearable3,241 steps/day
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.2 · butyrate capacity 55/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    58 ms
    Sleep
    6.9 h
    Steps
    3,802
    Resting HR
    60 bpm
    Daily log: GI score 12, nutritional resilience 72, adherence 93.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0146758%S09HY-01improved79
    P-0143954%S18ME-01improved79
    P-0159153%S0381
    P-0164553%S0682
    P-0138252%S1582
    P-0142250%S1680
    P-0175950%S1978
    P-0138049%S1780
    P-0167149%S04SC-12improved90
    P-0167349%S0476
    P-0171749%S1876
    P-0187649%S1984