Patient P-01576
Therapy response
Improving
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
71%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 No meaningful change — Dietary Support Protocol NP-02
- Day 45 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 55 GI-04 recommended — GI Support Protocol GI-04
- Day 56 Patient accepted — Started GI-04 in the companion
- Day 64 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 45.
Primary contributors, last 14 days
- GI instability-13
- Inflammatory activity-13
- Nutritional resilience+8
- Toxicity-6
- Treatment adherence+4
What helped?
- Dietary Support Protocol NP-02Day 31Result: no meaningful change
- GI Support Protocol GI-04Day 55Result: no meaningful change
LIFE OS recommendation
Monitoring Escalation ME-01
81%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion52.9/100
stable · -0.9 vs previous 14 d
Toxicity
Blood51.5/100
improving · -2.5 vs previous 14 d
Sleep quality
Wearable1.7/100
improving · +2.8 vs previous 14 d
Energy level
Daily log2.1/10
improving · +0.2 vs previous 14 d
Stress level
Daily log6.6/10
stable · -0.3 vs previous 14 d
Steps
Wearable3,423
worsening · -507 vs previous 14 d
Adherence
Companion44.1 %
worsening · -2.2 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 33 from the failing basin, 55 from restoration.
Would help
Would not help
- GI-04 GI Support Protocolalready tried, no meaningful change
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep fat lowGI +2.1 next day on high-intake days · n 21
- Keep fibre lowGI +1.5 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+2.1detractor · 86%
- Insoluble fibre+1.5detractor · 56%
- Histamine load+1.1no signal · 48%
- Simple carbohydrates-1.1no signal · 38%
- Spicy / capsaicin+1.1no signal · 45%
- Alcohol+0.9no signal · 31%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 54
- WearableHRV 22 ms, trending down
- Autonomic recovery ↑65
- WearableResting HR 73 bpm
- Wearable3,423 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 53 and rising
- WearableSleep 5.1 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑20
- BloodToxicity index 52
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 17 ms
- Sleep
- 5.1 h
- Steps
- 3,032
- Resting HR
- 76 bpm
Daily log: GI score 53, nutritional resilience 43, adherence 44.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.