600 patients66,869 observations120 daysLIVE

Patient P-01590

Synthetic patientNBL-101 · Day 113 · 25–34 · F · baseline S19Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
12%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S19

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • Toxicity-9
  • Inflammatory activity-7
  • GI instability-3
  • Treatment adherence-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    19.1/100
    stable · -0.7 vs previous 14 d
    Toxicity
    Blood
    11.9/100
    improving · -2.5 vs previous 14 d
    Sleep quality
    Wearable
    46.4/100
    improving · +6.5 vs previous 14 d
    Energy level
    Daily log
    6.5/10
    improving · +0.5 vs previous 14 d
    Stress level
    Daily log
    4.2/10
    improving · -0.5 vs previous 14 d
    Steps
    Wearable
    7,524
    stable · +230 vs previous 14 d
    Adherence
    Companion
    90.7 %
    improving · +3.9 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 76 from the failing basin, 19 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Daily walks resumed
      perturbation · steering +3.3
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • Antibiotic course
      perturbation · steering -4.7
    • Poor-sleep week
      perturbation · steering -3
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Insoluble fibre
      +1no signal · 28%
    • Alcohol
      +0.8no signal · 25%
    • Spicy / capsaicin
      -0.7no signal · 21%
    • Simple carbohydrates
      -0.6no signal · 18%
    • Dietary fat load
      +0.5no signal · 15%
    • Histamine load
      -0.4no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure 75
      • DNACYP2D6 poor metabolizer → higher exposure
      • DNADPYD *2A → slower clearance
    • Inflammatory signalling 35
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 34 ms, trending down
    • Mucosal barrier integrity 30
      • MicrobiomeAkkermansia low → thinner mucus layer
    DNA
    Fictional pharmacogenomic panel
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 3.8 · butyrate capacity 53/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    32 ms
    Sleep
    7.9 h
    Steps
    7,849
    Resting HR
    68 bpm
    Daily log: GI score 19, nutritional resilience 62, adherence 91.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0143454%S1853
    P-0180954%S1155
    P-0169352%S0562
    P-0143050%S05CR-01improved54
    P-0168450%S1359
    P-0180450%S19AD-05improved61
    P-0181450%S1960
    P-0181550%S0957
    P-0152649%S1452
    P-0153749%S0453
    P-0153849%S1556
    P-0141848%S0466