Patient P-01597

Synthetic patientNBL-101 · Day 120 · 35–44 · F · baseline S14Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Unstable

GI state

Unstable

Inflammatory state

Unstable

Nutritional resilience

Unstable

Discontinuation risk

89%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S14
Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 57 GI-04 recommended — GI Support Protocol GI-04
Day 58 Patient accepted — Started GI-04 in the companion
Day 66 No meaningful change — GI Support Protocol GI-04

What changed?

Trajectory began diverging from predicted response on Day 47.

Primary contributors, last 14 days

Treatment adherence+9
Inflammatory activity+5
Toxicity+3

What helped?

GI Support Protocol GI-04Day 57
Result: no meaningful change

LIFE OS recommendation

Dietary Support Protocol NP-02

59%

probability of meaningful tolerance improvement

284 similar trajectories
66% showed improvement
median effect visible after 10 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

79.2/100

improving · -3.8 vs previous 14 d

Toxicity

Blood

61.3/100

worsening · +8.9 vs previous 14 d

Sleep quality

Wearable

3.7/100

improving · +5.2 vs previous 14 d

Energy level

Daily log

0.4/10

improving · +0.1 vs previous 14 d

Stress level

Daily log

8.7/10

stable · +0.2 vs previous 14 d

Steps

Wearable

340

stable · +14 vs previous 14 d

Adherence

Companion

46.7 %

stable · +0.4 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 23 from the failing basin, 86 from restoration.

Would help

ME-01 Monitoring Escalation
100% improved among 77 similar · onset 3 d · confidence 71%
NP-02 Dietary Support Protocol
63% improved among 64 similar · onset 10 d · confidence 71%
SC-12 Supportive Compound
76% improved among 51 similar · onset 6 d · confidence 71%

Would not help

GI-04 GI Support Protocol
already tried, no meaningful change
Keep fat low
GI +4.2 next day on high-intake days · n 22
Keep simple carbs low
GI +2.8 next day on high-intake days · n 22

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+4.2detractor · 95%
Simple carbohydrates
+2.8detractor · 85%
Insoluble fibre
+1.1no signal · 33%
Spicy / capsaicin
-0.9no signal · 24%
Alcohol
-0.8no signal · 25%
Histamine load
-0.6no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↓65
- WearableResting HR 74 bpm
- Wearable340 steps/day
- WearableShort sleep window
Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 79 and rising
- WearableSleep 5.2 h, below personal baseline
Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 40/100
- Daily logFibre intake low in recent food logs
Inflammatory signalling ↑40
- BloodInflammatory load index 71
- WearableHRV 15 ms, trending down
Drug metabolism and exposure ↑20
- BloodToxicity index 61

DNA

Fictional pharmacogenomic panel

CYP2D6 Rapid metabolizer
Expected exposure

Microbiome

Shannon diversity 2.7 · butyrate capacity 40/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 15 ms
Sleep: 5.6 h
Steps: 477
Resting HR: 73 bpm

Daily log: GI score 79, nutritional resilience 30, adherence 47.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Track each bowel movement today: time, stool form, urgency, overnight waking
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
Electrolyte solution, one sachet after any loose stool
Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01854	48%	S14	ME-01	improved	46
P-01615	43%	S14	ME-01	improved	48
P-01656	42%	S14	ME-01	improved	41
P-01720	42%	S14	NP-02	improved	47
P-01810	42%	S05	NP-02	improved	43
P-01728	41%	S14	SC-12	improved	41
P-01736	41%	S03	ME-01	improved	46
P-01739	41%	S14	ME-01	improved	44
P-01492	40%	S15	ME-01	improved	44
P-01605	40%	S14	ME-01	improved	41
P-01872	40%	S14	NP-02	improved	47
P-01897	40%	S14	ME-01	improved	43