Patient P-01600
Synthetic patientNBL-101 · Day 116 · 35–44 · F · baseline S06Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
54%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S06
- Day 81 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 82 CR-01 recommended — Clinician Review CR-01
- Day 83 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 81.
Primary contributors, last 14 days
- GI instability-10
- Inflammatory activity-7
- Nutritional resilience+6
- Treatment adherence-6
What helped?
- Clinician Review CR-01Day 82Declined by patient
LIFE OS recommendation
GI Support Protocol GI-04
54%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion49.6/100
improving · -2.4 vs previous 14 d
Toxicity
Blood57.5/100
worsening · +8.1 vs previous 14 d
Sleep quality
Wearable14.1/100
improving · +2.0 vs previous 14 d
Energy level
Daily log3.3/10
worsening · -0.1 vs previous 14 d
Stress level
Daily log7.2/10
stable · +0.1 vs previous 14 d
Steps
Wearable3,582
stable · -28 vs previous 14 d
Adherence
Companion63.9 %
worsening · -10.2 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 36 from the failing basin, 52 from restoration.
Good elements to keep
- Stable without identifiable pulls.
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- FUT2 non-secretorhidden · steering -10.6
- Dietary fat loadperturbation · steering -9
- Histamine loadperturbation · steering -7.8
- Dietary fat loaddetractor · GI +4.8 next day
- Histamine loaddetractor · GI +4.6 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.8detractor · 95%
- Histamine load+4.6detractor · 95%
- Simple carbohydrates-1.6no signal · 43%
- Spicy / capsaicin-1no signal · 22%
- Alcohol+0.8no signal · 22%
- Insoluble fibre+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 53
- WearableHRV 37 ms, trending down
- Autonomic recovery ↑65
- WearableResting HR 79 bpm
- Wearable3,582 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 50 and rising
- WearableSleep 5.3 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 40/100
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑20
- BloodToxicity index 58
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3 · butyrate capacity 40/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 29 ms
- Sleep
- 5.3 h
- Steps
- 2,924
- Resting HR
- 81 bpm
Daily log: GI score 50, nutritional resilience 46, adherence 64.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.